Theaflavin-3,3′-Digallate Inhibits Erastin-Induced Chondrocytes Ferroptosis via the Nrf2/GPX4 Signaling Pathway in Osteoarthritis
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DOI: 10.1155/2022/3531995
Abstract: There is evidence that osteoarthritis (OA) is associated with ferroptosis which is a kind of lipid peroxidation-related cell death. Theaflavin-3,3′-digallate(TF3), a polyphenol compound extracted from black tea, possesses antioxidative and anti-inflammatory properties, but its effects… read more here.
Keywords: nrf2 gpx4; signaling pathway; gpx4 signaling; gpx4 ... See more keywords
Activation of the Nrf2/GPX4 Signaling by Pratensein From Trifolium pretense Mitigates Ferroptosis in OGD/R-Insulted H9c2 Cardiomyocytes
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DOI: 10.1177/1934578x221115313
Abstract: Background: Pratensein (PTS) is a type of flavonoid that has been identified in various plants, such as Trifolium pretense L., with a considerable cytoprotective effect against exogenous stimuli. However, the biological function of PTS in… read more here.
Keywords: nrf2 gpx4; gpx4 signaling; h9c2 cells; h9c2 ... See more keywords