Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
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DOI: 10.1016/j.redox.2017.01.021
Abstract: Synaptic loss and neuron death are the underlying cause of neurodegenerative diseases such as Alzheimer's disease (AD); however, the modalities of cell death in those diseases remain unclear. Ferroptosis, a newly identified oxidative cell death… read more here.
Keywords: forebrain neurons; gpx4biko mice; glutathione peroxidase; neurodegeneration ... See more keywords