Missing GPx8 activity in ER impacts on lipid composition
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DOI: 10.1016/j.freeradbiomed.2018.04.428
Abstract: Cys-containing GPx8 is an intrinsic ER enzyme, whose silencing leads to H2O2 leakage. While studying GPx8 in HeLa cells, we observed that enzyme silencing deeply impacts on ER membrane lipid composition. ESI-Q-TOF-MS, integrated with principal… read more here.
Keywords: gpx8; gpx8 activity; lipid composition; missing gpx8 ... See more keywords
GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma
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DOI: 10.1155/2022/8025055
Abstract: One of the most prevalent malignant primary brain tumors is primary glioma. Although glutathione peroxidase 8 (GPX8) is intimately associated with carcinogenesis, its function in primary gliomas has not yet been thoroughly understood. Here, we… read more here.
Keywords: therapeutic target; primary glioma; gpx8; expression ... See more keywords
A Comprehensive Analysis of the Glutathione Peroxidase 8 (GPX8) in Human Cancer
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DOI: 10.3389/fonc.2022.812811
Abstract: Objective Nowadays, cancer is still a leading public health problem all over the world. Several studies have reported the GPX8 could be correlated with the poor prognostic of Gastric Cancer and Breast Cancer. However, the… read more here.
Keywords: expression; cancer; gpx8 human; gbm ... See more keywords
Immunohistochemistry and Bioinformatics Identify GPX8 as a Potential Prognostic Biomarker and Target in Human Gastric Cancer
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DOI: 10.3389/fonc.2022.878546
Abstract: Background Glutathione peroxidase 8 (GPX8) is a type II transmembrane protein with rare structural features belonging to the glutathione peroxidase family. The function of GPX8 in stomach adenocarcinoma has not been discovered clearly. Methods In… read more here.
Keywords: gpx8; stomach adenocarcinoma; database; expression ... See more keywords