Asymmetric Total Synthesis of (–)-Gracilamine Using a Bioinspired Approach
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DOI: 10.1002/ejoc.201701474
Abstract: The asymmetric total synthesis of optically pure (–)-gracilamine (1) was achieved by employing a bioinspired approach. The strategy involved elaboration of 3a-arylhexahydroindole 7, a designed precursor, to 3a-formylarylhexahydroindole 5, which upon heating with l-leucine ethyl… read more here.
Keywords: asymmetric total; total synthesis; gracilamine; bioinspired approach ... See more keywords