Subventricular zone predicts high velocity of tumor expansion and poor clinical outcome in patients with low grade astrocytoma
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2018.02.036
Abstract: OBJECTIVE The aim of this study is to clarify the association between subventricular zone (SVZ) involvement and velocity of diametric expansion(VDE) in patients with low-grade astrocytoma and also assessed the clinical outcome of those patients.… read more here.
Keywords: svz involvement; patients low; grade astrocytoma; vde ... See more keywords
Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2018.03.047
Abstract: Epileptic seizures are the main clinical manifestation of low-grade astrocytoma. Voltage-gated sodium channels (VGSCs) play a crucial role in epilepsy. Until now, the role of VGSCs and the relationships between calmodulin (CaM)/CaM-dependent protein kinase II… read more here.
Keywords: low grade; grade astrocytoma; nav1 nav1;
Impact of Resection on Survival of Isocitrate Dehydrogenase 1-Mutated World Health Organization Grade II Astrocytoma After Malignant Progression.
Sign Up to like & getrecommendations! Published in 2017 at "World neurosurgery"
DOI: 10.1016/j.wneu.2017.03.123
Abstract: OBJECTIVE To evaluate the impact of surgical resection and adjuvant treatment on the course of patients after malignant progression of previously treated isocitrate dehydrogenase 1 (IDH1)-mutated World Health Organization (WHO) grade II astrocytoma. METHODS This… read more here.
Keywords: world; malignant progression; resection; grade astrocytoma ... See more keywords
Clinical, Histological and Molecular Features of Gliomas in Adults with Neurofibromatosis Type 1.
Sign Up to like & getrecommendations! Published in 2023 at "Neuro-oncology"
DOI: 10.1093/neuonc/noad033
Abstract: BACKGROUND People with NF1 have an increased prevalence of CNS malignancy. However, little is known about the clinical course or pathologic features of NF1-associated gliomas in adults, limiting clinical care and research. METHODS Adults (≥18… read more here.
Keywords: gliomas adults; clinical histological; grade astrocytoma; gliomas ... See more keywords
P13.12.B POST-PROGRESSION SURVIVAL FOLLOWING FOCAL RE-IRRADIATION WITH 20 GY IN 5 FRACTIONS IN PROGRESSIVE CNS WHO GRADE 3 ASTROCYTOMA AND GLIOBLASTOMA - A MONOCENTRIC RETROSPECTIVE ANALYSIS
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae144.245
Abstract: Despite multimodal treatment (resection, radiation therapy, alkylating chemotherapy and/or tumor-treating fields), the treatment of progressive CNS WHO Grade 3 astrocytoma and glioblastoma remains challenging. Re-irradiation (Re-RT) might be considered in the course of the disease.… read more here.
Keywords: astrocytoma; treatment; astrocytoma glioblastoma; progression ... See more keywords
CTNI-32. VORASIDENIB IN CHINESE PATIENTS WITH IDH1/2-MUTANT GRADE 2 ASTROCYTOMA OR OLIGODENDROGLIOMA: THE EARLIEST REAL-WORLD CASES IN ASIA
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.0528
Abstract: Vorasidenib (VOR), a brain-penetrant dual inhibitor of mutant IDH1/2 (mIDH1/2), is US.FDA-approved for Grade 2 mIDH1/2 diffuse glioma but has not yet been approved in Asia. Clinical evidence in Asian populations remains limited. Leveraging the… read more here.
Keywords: grade; grade astrocytoma; mutation; case ... See more keywords
QOL-01. A Propensity-Score Matched Prospective Study on the Impact of TTFields on Overall Survival and Quality of Life in Newly Diagnosed WHO Grade 4 Astrocytoma Patients
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1503
Abstract: Tumour treating fields (TTF) has been shown to improve overall survival (OS) for patients with WHO grade 4 astrocytoma, but few explored quality-of-life (QoL) in these patients. This was a prospective multi-center study of adult… read more here.
Keywords: ttf; diagnosed grade; propensity score; group ... See more keywords
A case of high‐grade astrocytoma with BRAF and ATRX mutations following a long‐standing course over two decades
Sign Up to like & getrecommendations! Published in 2017 at "Neuropathology"
DOI: 10.1111/neup.12370
Abstract: Pediatric high‐grade gliomas are rare and occasionally hard to classify. These tumors often feature a well‐demarcated histology and are expected to have a better outcome than ordinary diffuse high‐grade gliomas in adults. We herein report… read more here.
Keywords: grade; high grade; grade astrocytoma; case ... See more keywords
Isocitrate Dehydrogenase-Mutant WHO Grade 4 Astrocytoma with BCOR Alteration: Case Report
Sign Up to like & getrecommendations! Published in 2025 at "Case Reports in Oncology"
DOI: 10.1159/000548555
Abstract: Abstract Introduction: BCOR, a transcriptional regulator and component of the noncanonical polycomb repressive complex 1 (PRC1), plays an important role in tumorigenesis through transcriptional repression mediated by histone modifications. Alterations in BCOR, including nonsense, frameshift,… read more here.
Keywords: oncology; mutant grade; grade astrocytoma; bcor ... See more keywords
High-grade astrocytoma in a sheep: clinical, pathology, and genetic investigations
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/10406387251318694
Abstract: Primary neoplastic diseases of the CNS in livestock are rare compared to companion animals. Here we describe the clinical, pathologic, and genetic findings in an adult sheep with a high-grade cerebral astrocytoma. Clinically, apathy, ataxia,… read more here.
Keywords: grade astrocytoma; astrocytoma sheep; pathology; high grade ... See more keywords
High-grade astrocytoma with piloid features: a single-institution case series and literature review
Sign Up to like & getrecommendations! Published in 2025 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-025-01987-0
Abstract: High-grade astrocytoma with piloid features (HGAP) is a recently described primary brain tumor and the first requiring a specific methylation pattern for diagnosis, as its histologic features are often compatible with other tumors such as… read more here.
Keywords: case series; high grade; piloid features; grade astrocytoma ... See more keywords