Trehalose causes low-grade lysosomal stress to activate TFEB and the autophagy-lysosome biogenesis response.
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DOI: 10.1080/15548627.2021.1896906
Abstract: The autophagy-lysosome system is an important cellular degradation pathway that recycles dysfunctional organelles and cytotoxic protein aggregates. A decline in this system is pathogenic in many human diseases including neurodegenerative disorders, fatty liver disease, and… read more here.
Keywords: system; autophagy lysosome; grade lysosomal; low grade ... See more keywords