Grade 1‐2 neutropenia after first treatment for diffuse large B‐cell lymphoma is associated with a better outcome compared to grade 3‐4—A Danish population‐based cohort study
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2439_71
Abstract: employed multivariate Cox proportional hazard models on selected clinical variables. Training was performed on defined sets of cases identified molecularly similar for each individual case, and on all cases in the database; Cox proportional hazard… read more here.
Keywords: neutropenia first; treatment diffuse; grade neutropenia; cell ... See more keywords
Grade 4 Neutropenia Frequency as a Binary Risk Predictor for Adverse Clinical Consequences of Chemotherapy‑Induced Neutropenia: A Meta-analysis
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Investigation"
DOI: 10.1080/07357907.2023.2179064
Abstract: Abstract Neutropenia is the major toxicity of myelosuppressive cancer chemotherapy. Grade 4 neutropenia (Gr4N) is a measure of chemotherapy-induced neutropenia (CIN) severity. We conducted a meta-analysis of CIN data. Gr4N incidence was significantly correlated with… read more here.
Keywords: chemotherapy induced; grade neutropenia; induced neutropenia; cin ... See more keywords
A case of severe Pembrolizumab-induced neutropenia.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000661
Abstract: Immune checkpoint inhibitors have revolutionized cancer therapy. Given their mechanism of action, immune-related adverse events have been associated with their use. We present the first documented case of pembrolizumab-induced grade IV neutropenia. A 73-year-old women… read more here.
Keywords: case; grade neutropenia; pembrolizumab induced; pembrolizumab ... See more keywords
Streptococcal Infections and Exacerbation in Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection: A Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Infectious Disease Journal"
DOI: 10.1097/inf.0000000000002310
Abstract: Z et al in their article emphasize the hematologic adverse effects among infants with congenital cytomegalovirus infection treated with valganciclovir. We have cared over 12 years for 156 infants with congenital cytomegalovirus infection. Nineteen of… read more here.
Keywords: grade neutropenia; ganciclovir valganciclovir; infections exacerbation; infection ... See more keywords
A randomized, multicenter phase III Study of once-per-cycle administration of efbemalenograstim alfa (F-627), a novel long-acting rhG-CSF, for prophylaxis of chemotherapy-induced neutropenia in patients with breast cancer
Sign Up to like & getrecommendations! Published in 2024 at "BMC Cancer"
DOI: 10.1186/s12885-024-12892-5
Abstract: F-627 (efbemalenograstim alfa) is a novel long acting granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2) -Fc fragment with a peptide linker. This studyevaluated the efficacy and… read more here.
Keywords: grade neutropenia; efbemalenograstim alfa; group; novel long ... See more keywords
Guard-02: Safety and efficacy of prophylactic use of novel long-acting G-CSF efbemalenograstim α on same-day of chemotherapy in breast cancer patients.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e24088
Abstract: e24088 Background: Granulocyte colony-stimulating factor (G-CSF) is widely used for prevention of chemotherapy-induced neutropenia (CIN), there is controversy over whether G-CSF can be given within 24 hours after chemotherapy yet. Efbemalenograstim α is a novel… read more here.
Keywords: hours chemotherapy; acting csf; long acting; grade neutropenia ... See more keywords
Grade 4 Neutropenia Secondary to Immune Checkpoint Inhibition — A Descriptive Observational Retrospective Multicenter Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.765608
Abstract: Introduction Immune checkpoint inhibitors (ICI) are increasingly being used to treat numerous cancer types. Together with improved recognition of toxicities, this has led to more frequent identification of rare immune-related adverse events (irAE), for which… read more here.
Keywords: immune checkpoint; ici; treatment; grade neutropenia ... See more keywords
Pharmacokinetic Variability Drives Palbociclib-Induced Neutropenia in Metastatic Breast Cancer Patients: Drug–Drug Interactions Are the Usual Suspects
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DOI: 10.3390/pharmaceutics14040841
Abstract: Palbociclib is a good candidate for therapeutic drug monitoring (TDM) due to its narrow therapeutic range and frequency of toxicities, particularly high-grade neutropenia. In this prospective, bicentric clinical trial, we evaluated the palbociclib exposure–toxicity relationship… read more here.
Keywords: high grade; grade neutropenia; palbociclib; drug ... See more keywords
Correlation Between Body Weight and Mitoxantrone-Associated Neutropenia in Dogs.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Animal Hospital Association"
DOI: 10.5326/jaaha-ms-6545
Abstract: Thirty-seven dogs with histologically or cytologically confirmed malignant tumors treated with single-agent mitoxantrone at 5 mg/m2 were evaluated in a retrospective study assessing the correlation between body weight and neutropenia associated with a single dose… read more here.
Keywords: correlation body; grade neutropenia; mitoxantrone; body weight ... See more keywords