Retention characteristics of some antibiotic and anti-retroviral compounds in hydrophilic interaction chromatography using isocratic elution, and gradient elution with repeatable partial equilibration.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.08.051
Abstract: The separation of some zwitterionic, basic and neutral antibiotic and antiretroviral compounds was studied using hydrophilic interaction chromatography (HILIC) on bare silica, bonded amide and urea superficially porous phases. The differences in the selectivity and… read more here.
Keywords: partial equilibration; equilibration; elution; hydrophilic interaction ... See more keywords
Generic approach in a gradient elution HPLC method development that enables troubleshooting free method transfer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2021.114367
Abstract: Nowadays, method development is strongly focused on reducing time needed for method development and execution. This subject specially concerns gradient elution methods regarding the usual need for troubleshooting assistance with uncertain outcome during the method… read more here.
Keywords: methodology; gradient elution; method development; method ... See more keywords
Temperature Gradient Elution and Superheated Eluents in Chip-HPLC.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b00142
Abstract: Utilizing temperature as an active parameter for optimization in chip-based liquid chromatography is an important step toward high-speed and high-efficiency separations on the microscale. A device including a low thermal mass micro thermostat and a… read more here.
Keywords: elution superheated; gradient elution; temperature gradient; chip ... See more keywords
A Microwave Flow Detector for Gradient Elution Liquid Chromatography.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b01924
Abstract: This study presents a microwave flow detector technique for liquid chromatography (LC) application. The detector is based on a tunable microwave interferometer (MIM) with a vector network analyzer (VNA) for signal measurement and a computer… read more here.
Keywords: microwave flow; detector; gradient elution; liquid chromatography ... See more keywords
Separation and Detection of Trace Fentanyl from Complex Mixtures Using Gradient Elution Moving Boundary Electrophoresis.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03083
Abstract: The current opioid epidemic remains an ongoing challenge, exacerbated by the extreme potency of synthetic opioids (e.g., fentanyl and fentanyl analogues), leading to an increase in adulterated heroin-related deaths. The increasing prevalence of fentanyl and… read more here.
Keywords: detection; elution moving; separation; gradient elution ... See more keywords
Determination of lovastatin, mevastatin, rosuvastatin and simvastatin with HPLC by means of gradient elution.
Sign Up to like & getrecommendations! Published in 2019 at "Die Pharmazie"
DOI: 10.1691/ph.2019.8192
Abstract: A novel HPLC method with UV detection was developed and validated in skin penetration (in vitro) studies to identify and quantify lovastatin, mevastatin, rosuvastatin and simvastatin. A Venusil XBP C18 (2), 150 x 4.6 mm,… read more here.
Keywords: hplc; lovastatin mevastatin; mevastatin rosuvastatin; simvastatin ... See more keywords
Analysis of Organic Impurities of Besifloxacin Hydrochloride by High-Performance Liquid Chromatography with Isocratic and Gradient Elution
Sign Up to like & getrecommendations! Published in 2019 at "Current Pharmaceutical Analysis"
DOI: 10.2174/1573412916666191022154543
Abstract: Impurity analysis is an important step in the quality control of pharmaceutical ingredients and the final product. Impurities can arise from drug synthesis or excipients and even at small concentrations may affect product efficacy and… read more here.
Keywords: elution; analysis; gradient elution; liquid chromatography ... See more keywords