Articles with "grail" as a keyword



Photo from wikipedia

Crustal density and global gravitational field estimation of the Moon from GRAIL and LOLA satellite data

Sign Up to like & get
recommendations!
Published in 2020 at "Planetary and Space Science"

DOI: 10.1016/j.pss.2020.105032

Abstract: Abstract We employ Newton's integral in the spectral domain to solve two geodetic/geophysical tasks for the Moon. Firstly, we determine 3D bulk density distribution within the lunar crust (inverse problem). For this purpose, we develop… read more here.

Keywords: satellite; gravitational field; density; model ... See more keywords
Photo from wikipedia

Absence of Grail promotes CD8+ T cell anti-tumour activity

Sign Up to like & get
recommendations!
Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00252-w

Abstract: T-cell tolerance is a major obstacle to successful cancer immunotherapy; thus, developing strategies to break immune tolerance is a high priority. Here we show that expression of the E3 ubiquitin ligase Grail is upregulated in… read more here.

Keywords: cd8 cells; anti tumour; grail; grail promotes ... See more keywords
Photo by lucabravo from unsplash

How GRAIL controls Treg function to maintain self-tolerance

Sign Up to like & get
recommendations!
Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1046631

Abstract: Regulatory T cells (Tregs) normally maintain self-tolerance. Tregs recognize “self” such that when they are not working properly, such as in autoimmunity, the immune system can attack and destroy one’s own tissues. Current therapies for… read more here.

Keywords: function; treg function; grail; drug ... See more keywords