Absence of Grail promotes CD8+ T cell anti-tumour activity
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DOI: 10.1038/s41467-017-00252-w
Abstract: T-cell tolerance is a major obstacle to successful cancer immunotherapy; thus, developing strategies to break immune tolerance is a high priority. Here we show that expression of the E3 ubiquitin ligase Grail is upregulated in… read more here.
Keywords: cd8 cells; anti tumour; grail; grail promotes ... See more keywords