Grainyhead‐like‐2 confers NK‐sensitivity through interactions with epigenetic modifiers
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2018.11.006
Abstract: HighlightsGRHL2 is a master programmer of the epithelial phenotype that sensitized cells to NK killing at the level of NK‐target cell synaptogenesis.Sensitization was mediated by the up‐regulation of ICAM‐1.GRHL2‐KMT2C/D interactions and p300 inhibition were important… read more here.
Keywords: epithelial phenotype; grainyhead like; expression; target cell ... See more keywords
Grainyhead-like transcription factors in cancer – Focus on recent developments
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DOI: 10.1177/1535370220903009
Abstract: The role of grainyhead-like transcription factors in cancer has been widely investigated by the scientific community. However, some of its aspects do not seem to be adequately appreciated, and these are the topic of our… read more here.
Keywords: grhl genes; grainyhead like; like transcription; cancer ... See more keywords
Spotlight on the Granules (Grainyhead-Like Proteins) – From an Evolutionary Conserved Controller of Epithelial Trait to Pioneering the Chromatin Landscape
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00213
Abstract: Among the transcription factors that are conserved across phylogeny, the grainyhead family holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead (grh) gene is essential during developmental processes such… read more here.
Keywords: chromatin; grainyhead like; grhl factors; chromatin landscape ... See more keywords