Gramine-based structure optimization to enhance anti-gastric cancer activity.
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DOI: 10.1016/j.bioorg.2020.104549
Abstract: Gramine is a natural indole alkaloid with a wide range of biological activities, but its anti-gastric cancer activity is poor. Herein, a pharmacophore fusion strategy was adopted to design and synthesize a new series of… read more here.
Keywords: gastric cancer; cancer; gramine based; anti gastric ... See more keywords