1255. In Vitro Activity of Vancapticin against Methicillin-Resistant Staphylococcus aureus from Periprosthetic Joint Infection
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DOI: 10.1093/ofid/ofaa439.1439
Abstract: The vancapticins are modified vancomycin derivatives developed by adding membrane targeting motifs to the C-terminus of vancomycin. We determined the in vitro activity of a lead vancapticin candidate against periprosthetic joint infection-associated methicillin-resistant Staphylococcus aureus… read more here.
Keywords: research support; vitro activity; consultant; grant research ... See more keywords
138. Focused Outpatient Antibiograms: Time for Widespread Implementation?
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DOI: 10.1093/ofid/ofaa439.183
Abstract: Significant antimicrobial use occurs in outpatient settings, making this an important area for expanding stewardship. Data show over 260 million annual prescriptions in the U.S. Family practitioners prescribed the most antibiotic courses (24%)1. Urinary Tract… read more here.
Keywords: scientific research; research; research support; survey ... See more keywords
224. Effect of Easing Overnight Restrictions on Antimicrobial Starts
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DOI: 10.1093/ofid/ofaa439.268
Abstract: Some institutions allow administration of restricted antibiotics overnight until evaluation the following day (i.e. first dose free) to adapt to limitations in personnel resources. Whether this method results in higher number of overnight requests compared… read more here.
Keywords: meropenem micafungin; number; week; grant research ... See more keywords
67. SARS-CoV-2 Transmission: Preliminary Findings from a Household-based Study
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DOI: 10.1093/ofid/ofaa439.377
Abstract: Social distancing measures, such as shelter-in-place or stay-at-home orders, are recommended for control of community transmission of SARS-CoV-2. Few studies, however, have characterized the transmission of SARS-CoV-2 infections in households. We conducted a case-ascertained study… read more here.
Keywords: household; research; index; research support ... See more keywords
22. International Multicenter Study Comparing Cancer to Non-Cancer Patients with COVID-19: Impact of Risk Factors and Treatment Modalities on Outcome
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DOI: 10.1093/ofid/ofab466.022
Abstract: Abstract Background Given the limited collaborative international studies that evaluated COVID-19 in patients with cancer in comparison to patients without cancer, we aimed to determine the independent risk factors associated with increased 30-day mortality and… read more here.
Keywords: cancer; grant research; support; research support ... See more keywords
154. Circulation of Rhinovirus/Enterovirus Respiratory Infections in Children During 2020-21 in the United States
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DOI: 10.1093/ofid/ofab466.154
Abstract: Abstract Background Sharp declines in influenza and respiratory syncytial virus (RSV) circulation across the U.S. have been described during the pandemic in temporal association with community mitigation for control of severe acute respiratory syndrome coronavirus… read more here.
Keywords: support; research support; grant research; research ... See more keywords
297. Infectious Complications Associated with Tocilizumab Use in Patients Infected with SARS-CoV-2 at a Mid-Atlantic Hospital Consortium
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DOI: 10.1093/ofid/ofab466.499
Abstract: Abstract Background The IL-6 inhibitor Tocilizumab (TOCI) has been associated with infections in 5-8% of patients with Rheumatoid Arthritis. TOCI has now been recommended as a treatment option for select patients with COVID-19; however, the… read more here.
Keywords: financial material; support; material support; treatment ... See more keywords
308. Secondary Infections in Patients Requiring Extracorporeal Membrane Oxygenation (ECMO) for Severe Acute Respiratory Distress Syndrome (ARDS) due to COVID-19 Pneumonia (PNA)
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DOI: 10.1093/ofid/ofab466.510
Abstract: Abstract Background Rescue ECMO has been used worldwide in patients (pts) with ARDS caused by COVID-19. Bacterial super-infections affect 3.5-14.3% of hospitalized pts with COVID-19. Pts requiring ECMO may be at an increased risk of… read more here.
Keywords: support; research support; infection; grant research ... See more keywords
354. SARS-CoV-2 Viral Viability Culture and Sequencing from Immunocompromised Patients with Persistently Positive SARS-CoV-2 PCR Results
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DOI: 10.1093/ofid/ofab466.555
Abstract: Abstract Background Immunocompromised (IC) patients (pts) can have prolonged SARS-CoV-2 PCR positivity, even after resolution of COVID-19 symptoms. This study aimed to determine if viable virus could be detected in samples collected > 21 days… read more here.
Keywords: support; sars cov; research support; grant research ... See more keywords
476. A Global Survey of Countermeasures Against the COVID-19 Pandemic Among Solid Organ Transplant Centers
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DOI: 10.1093/ofid/ofab466.675
Abstract: Abstract Background Solid organ transplantation (SOT) profoundly impacts vulnerable recipients with chronic end organ diseases. The COVID-19 pandemic disrupted healthcare systems, including organ transplants. We aimed to evaluate the responses of SOT centers to COVID-19… read more here.
Keywords: individual involved; research support; involved self; grant research ... See more keywords
489. SARS-CoV-2 Seroprevalence and Antibody Response Among Pregnant People in Seattle, WA
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DOI: 10.1093/ofid/ofab466.688
Abstract: Abstract Background Antenatal care is a unique opportunity to assess SARS-CoV-2 seroprevalence and antibody response in pregnant people, including those with previously unknown infection. Methods Pregnant people were screened for SARS-CoV-2 IgG during antenatal care… read more here.
Keywords: igg; support; sars cov; grant research ... See more keywords