Basophil Activation Techniques: Staining of Exteriorized Granule Matrix.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0696-4_17
Abstract: The basis of traditional flow cytometry allergy diagnosis is measurement of the expression of basophilic surface activation and/or degranulation markers. Basophils, upon encounter with a specific allergen that cross-links surface FcRI-bound IgE antibodies, not only… read more here.
Keywords: basophil activation; granule matrix; staining exteriorized;
SNARE-dependent membrane fusion initiates α-granule matrix decondensation in mouse platelets.
Sign Up to like & getrecommendations! Published in 2018 at "Blood advances"
DOI: 10.1182/bloodadvances.2018019158
Abstract: Platelet α-granule cargo release is fundamental to both hemostasis and thrombosis. Granule matrix hydration is a key regulated step in this process, yet its mechanism is poorly understood. In endothelial cells, there is evidence for… read more here.
Keywords: decondensation; release; granule matrix; fusion ... See more keywords