Monitoring kinetics reveals critical parameters of IgA-dependent granulocyte-mediated anti-tumor cell cytotoxicity.
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DOI: 10.1016/j.jim.2019.112644
Abstract: Human IgA antibodies effectively engage myeloid cells for the FcαRI-dependent antibody-dependent cell-mediated cytotoxicity (ADCC) of tumor cells. Established methods to investigate ADCC are the 51chromium and Calcein release assays. Their critical limitations are the end-point… read more here.
Keywords: critical parameters; granulocyte mediated; cytotoxicity; cell ... See more keywords