A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.02.046
Abstract: The central pathogen-immune interface in tuberculosis is the granuloma, a complex host immune structure that dictates infection trajectory and physiology. Granuloma macrophages undergo a dramatic transition in which entire epithelial modules are induced and define… read more here.
Keywords: immune; type immune; epithelialization; granuloma formation ... See more keywords
A case report on dermal filler-related periorbital granuloma formation
Sign Up to like & getrecommendations! Published in 2019 at "Orbit"
DOI: 10.1080/01676830.2018.1477806
Abstract: ABSTRACT We report a case of a 49-year old East-Asian female who presented with delayed onset granuloma formation at the right medial lower eyelid area. The clinical and radiologic presentation with pathologic correlation following synthetic… read more here.
Keywords: filler related; dermal filler; report; granuloma formation ... See more keywords
Novel management of granuloma formation secondary to dermal filler: A multi‐modality approach
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.15579
Abstract: Dermal fillers for soft tissue augmentation have become increasingly popular among patients of all ages and ethnicities. With more widespread use, there has been an increased incidence of adverse reactions, one of which is the… read more here.
Keywords: management granuloma; formation secondary; novel management; dermal filler ... See more keywords
Pulmonary granuloma formation during latent Cryptococcus neoformans infection in C3HeB/FeJ mice involves progression through three immunological phases
Sign Up to like & getrecommendations! Published in 2025 at "mBio"
DOI: 10.1128/mbio.03610-24
Abstract: ABSTRACT Cryptococcus neoformans is a fungal pathogen that can cause lethal disease in immunocompromised patients. Immunocompetent host immune responses, such as formation of pulmonary granulomas, control the infection and prevent disseminated disease. Little is known… read more here.
Keywords: granuloma; c3heb fej; neoformans infection; formation ... See more keywords
PTX3 in Granuloma Formation and Sarcoidosis: Helping Macrophages Accept a “Complement”
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.202207-1277ed
Abstract: Sarcoidosis is a multisystem disease characterized by the accumulation of noncaseating granulomas in affected organs (1, 2). It is proposed to originate from a prolonged or dysregulated immune response to as yet undefined antigen(s) in… read more here.
Keywords: sarcoidosis; complement; ptx3; formation ... See more keywords
The Renin-Angiotensin-Aldosterone System Regulates Sarcoidosis Granulomatous Inflammation.
Sign Up to like & getrecommendations! Published in 2024 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202402-0265oc
Abstract: Rationale: Sarcoidosis is a granulomatous disorder of unclear cause notable for abnormal elevation of blood and tissue angiotensin converting enzyme 1 (ACE1) levels and activity. ACE1 regulates the renin-angiotensin-aldosterone system (RAAS), the terminal product of… read more here.
Keywords: sarcoidosis granulomatous; aldosterone; renin angiotensin; granuloma formation ... See more keywords
Defective Granuloma Formation in Elderly Infected Patients
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00189
Abstract: Granulomas are compact structures formed in tissues by the immune system in response to aggressions. The in vitro formation of granulomas using circulating mononuclear cells is an innovative method to easily assess the immune response… read more here.
Keywords: form granulomas; defective granuloma; granuloma formation; formation ... See more keywords
Th17-Inducing Cytokines IL-6 and IL-23 Are Crucial for Granuloma Formation during Experimental Paracoccidioidomycosis
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00949
Abstract: Paracoccidioidomycosis (PCM), a chronic granulomatous disease caused by the thermally dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii, has the highest mortality rate among systemic mycosis. The T helper 1-mediated immunity is primarily responsible for acquired… read more here.
Keywords: formation experimental; th17; granuloma formation; paracoccidioidomycosis ... See more keywords
The Intricate Process of Calcification in Granuloma Formation and the Complications Following M. tuberculosis Infection
Sign Up to like & getrecommendations! Published in 2025 at "Biomolecules"
DOI: 10.3390/biom15071036
Abstract: Mycobacterium tuberculosis—an acid-fast staining bacterium—is a serious global health challenge that can have both short-term and long-term complications. Although the immune response helps trap the infection, it can also cause necrosis and calcification, leading to… read more here.
Keywords: tuberculosis; infection; calcification granuloma; calcification ... See more keywords