An Expandable Mechanopharmaceutical Device (2): Drug Induced Granulomas Maximize the Cargo Sequestering Capacity of Macrophages in the Liver
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2541-z
Abstract: PurposeDrug-induced liver injuries (DILI) comprise a significant proportion of adverse drug reactions leading to hospitalizations and death. One frequent DILI is granulomatous inflammation from exposure to harmful metabolites that activate inflammatory pathways of immune cells… read more here.
Keywords: granulomatous inflammation; drug induced; drug; associated macrophages ... See more keywords
Granulomatosis with polyangiitis: a life‐threatening cause of granulomatous mastitis
Sign Up to like & getrecommendations! Published in 2020 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.16106
Abstract: A 65-year-old post-menopausal woman presented to the breast clinic with 6 months’ history of an asymptomatic lump at the 2 o’clock position of her left breast. She proceeded to a mammogram and ultrasound, which showed… read more here.
Keywords: granulomatous mastitis; granulomatosis polyangiitis; mastitis; granulomatous inflammation ... See more keywords
Granulomatous inflammation in BK polyomavirus–associated nephropathy
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DOI: 10.1111/tid.12939
Abstract: Evolving BK polyomavirus–associated nephropathy (BKPyVAN) is characterized by tubulointerstitial inflammation that closely resembles acute T‐cell–mediated allograft rejection if tubulitis is significant. The cellular composition of the inflammation varies during the course of BKPyVAN, and clusters… read more here.
Keywords: associated nephropathy; granulomatous inflammation; inflammation; polyomavirus associated ... See more keywords
A Role for CD154, the CD40 Ligand, in Granulomatous Inflammation
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DOI: 10.1155/2017/2982879
Abstract: Granulomatous inflammation is a distinctive form of chronic inflammation in which predominant cells include macrophages, epithelioid cells, and multinucleated giant cells. Mechanisms regulating granulomatous inflammation remain ill-understood. CD154, the ligand of CD40, is a key… read more here.
Keywords: granulomatous inflammation; inflammation role; inflammation; cd40 ... See more keywords
The Oral Delivery of Water-Soluble Phenol TS-13 Ameliorates Granuloma Formation in an In Vivo Model of Tuberculous Granulomatous Inflammation
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DOI: 10.1155/2021/6652775
Abstract: The redox-sensitive signaling system Keap1/Nrf2/ARE is a premier protective mechanism against oxidative stress that plays a key role in the pathogenesis and development of various diseases, including tuberculous granulomatous inflammation. We have previously reported that… read more here.
Keywords: tuberculous granulomatous; granulomatous inflammation; keap1 nrf2; water soluble ... See more keywords
Chronic Granulomatous Inflammation after CyPass® Implantation
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DOI: 10.1159/000505491
Abstract: A 65-year-old patient suffering from pseudoexfoliation glaucoma and multiple previous surgeries at the right eye underwent CyPass® explantation 19 months after CyPass® Micro-Stent implantation due to chronic inflammation in the anterior chamber. Histologically, a foreign… read more here.
Keywords: cypass; chronic granulomatous; granulomatous inflammation; inflammation cypass ... See more keywords
Anterior Pituitary Failure in Patients with Granulomatous Inflammation
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DOI: 10.1210/jendso/bvab048.1169
Abstract: Introduction: Langerhan cell histiocytosis (LCH) is a rare cause of eosinophilic granulomatous inflammation that can affect multiple organ systems, mainly diagnosed in children. Hypothalamic-pituitary axis involvement is well established and is the characteristic intracranial manifestation… read more here.
Keywords: anterior pituitary; granulomatous inflammation; failure; lch ... See more keywords
Interleukin-4 Receptor Alpha Expressing B Cells Are Essential to Down-Modulate Host Granulomatous Inflammation During Schistosomasis
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DOI: 10.3389/fimmu.2018.02928
Abstract: Schistosomiasis (bilharzia) is a parasitic helminth disease that can cause severe inflammatory pathology leading to organ damage in humans. Failure of the host to regulate egg-driven granulomatous inflammation causes host morbidity during chronic infection with… read more here.
Keywords: schistosomiasis; expressing cells; granulomatous inflammation; pathology ... See more keywords
Granulomatous inflammation in inborn errors of immunity
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DOI: 10.3389/fped.2023.1110115
Abstract: Granulomas have been defined as inflammatory infiltrates formed by recruitment of macrophages and T cells. The three-dimensional spherical structure typically consists of a central core of tissue resident macrophages which may merge into multinucleated giant… read more here.
Keywords: granulomas iei; inborn errors; granulomatous inflammation; granulomas ... See more keywords
Evaluation of polymerase chain reaction in space-occupying lesions of liver reported as granulomatous inflammation/tuberculosis on fine-needle aspiration cytology
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DOI: 10.4103/1742-6413.198815
Abstract: Background: Tubercular involvement of the liver is uncommon, but is a serious consideration in differential diagnosis of granulomatous conditions, especially in endemic regions like India. Objective: To assess the role of polymerase chain reaction (PCR)… read more here.
Keywords: granulomatous inflammation; reported granulomatous; tuberculosis; polymerase chain ... See more keywords