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Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1a0120-414r
Abstract: Neutropenia and impaired functions were common manifestation in antiretroviral therapy (ART) in both naïve and experienced PLWHA. Granulopoiesis can be divided into two phases: lineage determination and committed granulopoiesis. However, stage‐specific impairment of granulopoiesis in…
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Keywords:
art experienced;
art;
segmented neutrophils;
stage specific ... See more keywords
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Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0532-6
Abstract: Although several studies have shown that scorpion venoms cause a systemic inflammatory response syndrome, little is known about the contribution of the hematopoietic organs. The aim of this study was to investigate the effect of…
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Keywords:
state;
response;
androctonus australis;
australis hector ... See more keywords
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Published in 2017 at "Nature Genetics"
DOI: 10.1038/ng.3853
Abstract: Mammalian SWI/SNF complexes have critical roles in development and differentiation, and are implicated in the pathogenesis of several diseases; however, the mechanisms underpinning disease manifestation and the specificity of the subunits mutated are incompletely understood.…
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Keywords:
smarcd2 containing;
mswi snf;
snf complex;
granulopoiesis ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43345
Abstract: Extremely-low-frequency magnetic fields (ELF-MF) have been classified as “possibly carcinogenic” to humans on the grounds of an epidemiological association of ELF-MF exposure with an increased risk of childhood leukaemia. Yet, underlying mechanisms have remained obscure.…
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Keywords:
robustness epigenetic;
exposure;
exposure affects;
granulopoiesis ... See more keywords
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Published in 2018 at "mBio"
DOI: 10.1128/mbio.00933-18
Abstract: ABSTRACT Emergency granulopoiesis is a hematopoietic program of stem cell-driven neutrophil production used to counteract immune cell exhaustion following infection. Shigella flexneri is a Gram-negative enteroinvasive pathogen controlled by neutrophils. In this study, we use…
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Keywords:
infection;
shigella;
emergency granulopoiesis;
stem ... See more keywords
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Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220931043
Abstract: While neutrophil production in emergency states has been extensively studied, regulation of neutrophil homeostasis in the steady-state remained incompletely understood. We have shown that innate immune receptor toll-like receptor (TLR)4 and downstream TIR-domain-containing adapter-inducing interferon-β…
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Keywords:
oral intake;
steady state;
receptor;
granulopoiesis ... See more keywords
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Published in 2022 at "Blood"
DOI: 10.1182/blood.2022015724
Abstract: The erythroblastic island (EBI), composed of a central macrophage surrounded by maturing erythroblasts, is the erythroid precursor niche. Despite numerous studies, its precise composition is still unclear. Using multispectral imaging flow cytometry (IFC), in vitro…
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Keywords:
granulopoiesis;
terminal erythropoiesis;
bone marrow;
erythropoiesis ... See more keywords
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Published in 2017 at "Journal of Leukocyte Biology"
DOI: 10.1189/jlb.3a1216-538rr
Abstract: Responding to systemic demands in producing and replenishing end‐effector blood cells is predicated on the appropriate delivery and interpretation of extrinsic signals to the HSPCs. The data presented herein implicate the systemic, extracellular form of…
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Keywords:
negative systemic;
st6gal negative;
regulator granulopoiesis;
blood ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.961601
Abstract: During acute infectious and inflammatory conditions, a large number of neutrophils are in high demand as they are consumed in peripheral organs. The hematopoietic system rapidly responds to the demand by turning from steady state…
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Keywords:
granulopoiesis;
regulation emergency;
emergency granulopoiesis;
granulopoiesis infection ... See more keywords