Hypermethylation‐mediated downregulation of lncRNA PVT1 promotes granulosa cell apoptosis in premature ovarian insufficiency via interacting with Foxo3a
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30222
Abstract: Long noncoding RNA PVT1 is involved in the progression of female gynecological cancers. However, the role of PVT1 in ovarian granulosa cell apoptosis‐mediated premature ovarian insufficiency (POI) remains unclear. This study aims to elucidate the… read more here.
Keywords: granulosa cell; cell apoptosis; pvt1;
Effects of NEFAs during IVM on pig embryos from granulosa cell‐cocultured oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23548
Abstract: Circulating levels of nonesterified fatty acids (NEFAs) are elevated in some females, which can impair oocyte maturation and embryo development, and may alter the phenotype of the progeny. However, the effects of NEFAs on human… read more here.
Keywords: development; embryos; effects nefas; granulosa cell ... See more keywords
N‐acetyl cysteine‐mediated effective attenuation of methoxychlor‐induced granulosa cell apoptosis by counteracting reactive oxygen species generation in caprine ovary
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22221
Abstract: Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant‐targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study… read more here.
Keywords: granulosa; apoptosis; caprine ovary; granulosa cell ... See more keywords
Follicular factors determining granulosa cell number and developmental competence of porcine oocytes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-018-1247-9
Abstract: PurposeGranulosa cell (GC) number in follicles is a simple characteristic of follicles. The present study examined the hypothesis that follicular fluid (FF) determines GC number and oocyte developmental ability and revealed the molecular background determining… read more here.
Keywords: granulosa cell; number gcs; cell number; gcs ... See more keywords
MiR-21-5p actions at the Smad7 gene during pig ovarian granulosa cell apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2020.106645
Abstract: MicroRNAs (miRNAs) are endogenous non-coding RNAs in eukaryotic cells that modulate apoptosis of ovarian granulosa cells (GCs), which is an important cause of mammalian follicular atresia. In the present study, associations were evaluated between miR-21-5p… read more here.
Keywords: ovarian granulosa; mir actions; granulosa cell; apoptosis ... See more keywords
Adult testicular granulosa cell tumour: A rare case report
Sign Up to like & getrecommendations! Published in 2022 at "Urology Case Reports"
DOI: 10.1016/j.eucr.2021.101972
Abstract: Adult Granulosa cell tumours (AGT) are a rarely reported subtype of testicular cancer with an unpredictable clinical course. We report the case of a 45 year old man who was diagnosed with a 15mm testicular… read more here.
Keywords: cell tumour; case; adult; granulosa cell ... See more keywords
Role of adjuvant chemotherapy in the management of stage IC ovarian granulosa cell tumors
Sign Up to like & getrecommendations! Published in 2019 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2019.04.004
Abstract: Objective The aim of the present study was to investigate the patterns of use and prognostic significance of adjuvant chemotherapy (CT) for patients with stage IC ovarian granulosa cell tumors (GCTs). Methods We identified patients… read more here.
Keywords: chemotherapy; ovarian granulosa; adjuvant chemotherapy; granulosa cell ... See more keywords
Benign ovarian thecoma with markedly elevated serum inhibin B levels mimicking adult granulosa cell tumor
Sign Up to like & getrecommendations! Published in 2020 at "Gynecologic Oncology Reports"
DOI: 10.1016/j.gore.2020.100658
Abstract: Highlights • A rare case of markedly elevated inhibin B associated with an ovarian thecoma.• Inhibin B lacks specificity as a tumor marker for adult granulosa cell tumor.• A full differential for elevated Inhibin B… read more here.
Keywords: ovarian thecoma; adult granulosa; granulosa cell; markedly elevated ... See more keywords
Adult granulosa cell tumor with minor foci of juvenile granulosa cell tumor in postmenopausal woman: A rare case report.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of surgery case reports"
DOI: 10.1016/j.ijscr.2021.106531
Abstract: INTRODUCTION Granulosa cell tumor (GCT) is a rare neoplasm that is divided into adult GCT (AGCT) and juvenile GCT (JGCT). Generally, a patient will only have the AGCT or JGCT subtypes. Here, we presented the… read more here.
Keywords: granulosa cell; cell tumor; case; tumor ... See more keywords
miR-23b-3p inhibits chicken granulosa cell proliferation and steroid hormone synthesis via targeting GDF9.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.10.011
Abstract: MicroRNAs (miRNAs) are ∼22 nt RNAs that direct post-transcriptional repression of mRNA targets in diverse eukaryotic lineages. Granulosa cells (GCs) are the earliest differentiated follicular somatic cells. From the initiation of primordial follicles, their differentiation and… read more here.
Keywords: hormone synthesis; granulosa; granulosa cell; mir 23b ... See more keywords
Ovarian granulosa cell tumor: A National Cancer Database study.
Sign Up to like & getrecommendations! Published in 2017 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2017.05.020
Abstract: OBJECTIVE To provide prognostic information from a large cohort of women with granulosa cell tumor we analyzed the National Cancer Database. METHODS We performed an observational retrospective cohort analysis of 2680 women with ovarian granulosa… read more here.
Keywords: granulosa cell; cancer database; cell tumor; national cancer ... See more keywords