2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis
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DOI: 10.1371/journal.pntd.0010618
Abstract: 2-Deoxy-D-glucose (2-DG) is a glucose analog used as a promising anticancer agent. It exerts its effects by inhibiting the glycolytic energy metabolism to deplete cells of energy. The larval stage of Echinococcus relies on glycolysis… read more here.
Keywords: deoxy glucose; granulosus protoscoleces; echinococcus granulosus; echinococcus ... See more keywords
In Vitro Scolicidal Activity of the Sesquiterpenes Isofuranodiene, α-Bisabolol and Farnesol on Echinococcus granulosus Protoscoleces
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DOI: 10.3390/molecules25163593
Abstract: Cystic echinococcosis (CE) remains an important challenge both in humans and animals. There is no safe and suitable remedy for CE, so the discovery of new compounds with promising scolicidal effects, particularly from herbal sources,… read more here.
Keywords: farnesol; echinococcus granulosus; granulosus protoscoleces; scolicidal activity ... See more keywords