Articles with "granzyme inactivation" as a keyword



Photo by repponen from unsplash

Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation

Sign Up to like & get
recommendations!
Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/1557010

Abstract: Ischemic stroke is a devastating CNS insult with few clinical cures. Poor understanding of underlying mechanistic network is the primary limitation to develop novel curative therapies. Extracellular accumulation of granzyme B subsequent ischemia promotes neurodegeneration.… read more here.

Keywords: subsequent cerebral; granzyme inactivation; cerebral ischemia; granzyme ... See more keywords