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Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac094
Abstract: MOTIVATION Polypharmacy is the combined use of drugs for the treatment of diseases. However, it often shows a high risk of side effects. Due to unnecessary interactions of combined drugs, the side effects of polypharmacy…
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Keywords:
semantics;
multidirectional semantics;
graph embeddings;
side effects ... See more keywords
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Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz117
Abstract: SUMMARY Knowledge graph embeddings (KGEs) have received significant attention in other domains due to their ability to predict links and create dense representations for graphs' nodes and edges. However, the software ecosystem for their application…
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Keywords:
knowledge;
biokeen library;
knowledge graph;
graph embeddings ... See more keywords
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Published in 2022 at "Bioinformatics"
DOI: 10.1101/2022.02.25.481923
Abstract: Despite recent advancements in sequencing technologies and assembly methods, obtaining high-quality microbial genomes from metagenomic samples is still not a trivial task. Current metagenomic binners do not take full advantage of assembly graphs and are…
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Keywords:
graph;
assembly graph;
graph embeddings;
binning assembly ... See more keywords
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Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6272-2
Abstract: Semantic similarity between Gene Ontology (GO) terms is a fundamental measure for many bioinformatics applications, such as determining functional similarity between genes or proteins. Most previous research exploited information content to estimate the semantic similarity…
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Keywords:
terms proteins;
information;
similarity;
vector representations ... See more keywords