The risk factors for Graves’ ophthalmopathy
Sign Up to like & getrecommendations! Published in 2021 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05456-x
Abstract: This review aimed to provide an overview of current research into the risk factors for Graves’ ophthalmopathy (GO). To find information about the risk factors for GO, the research database PubMed was searched and relevant… read more here.
Keywords: risk; graves ophthalmopathy; research; risk factors ... See more keywords
The potential of tear proteomics for diagnosis and management of orbital inflammatory disorders including Graves' ophthalmopathy.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108813
Abstract: BACKGROUND Orbital compartments harbor a variety of tissues that can be independently targeted in a plethora of disorders resulting in sight-threatening risks. Orbital inflammatory disorders (OID) including Graves' ophthalmopathy, sarcoidosis, IgG4 disease, granulomatosis with polyangiitis,… read more here.
Keywords: graves ophthalmopathy; inflammatory disorders; disease; including graves ... See more keywords
An osteopathic approach to Graves’ ophthalmopathy: A case report
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Osteopathic Medicine"
DOI: 10.1016/j.ijosm.2020.01.002
Abstract: Abstract Grave's ophthalmopathy (GO), also known as Basedowian ophthalmopathy, is common and present in about 25–50% of Graves' disease patients. Graves' disease is an autoimmune disorder leading to excess thyroid hormone production. Patients may present… read more here.
Keywords: osteopathic approach; graves ophthalmopathy; approach graves; treatment ... See more keywords
Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy
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DOI: 10.1042/bsr20202072
Abstract: Abstract The macrophage migration inhibitory factor (MIF)/cluster of differentiation 74 (CD74) plays a role in immunological functions. The present study aims to investigate whether single-nucleotide polymorphisms (SNPs) in the MIF and CD74 are risk factors… read more here.
Keywords: differentiation; cluster differentiation; cd74; graves disease ... See more keywords
In Vivo Confocal Microscopy Morphometric Analysis of Meibomian Glands in Patients With Graves Ophthalmopathy.
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DOI: 10.1097/ico.0000000000002404
Abstract: PURPOSE To characterize meibomian glands (MGs) features in patients with Graves ophthalmopathy (GO) by in vivo confocal microscopy (IVCM) and to further investigate possible correlations with ocular surface characteristics. METHODS Consecutive patients with GO and… read more here.
Keywords: microscopy; vivo confocal; patients graves; meibomian glands ... See more keywords
Efficacy and safety of tripterygium glycosides for Graves ophthalmopathy
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DOI: 10.1097/md.0000000000018242
Abstract: BACKGROUND Graves ophthalmopathy (GO) is one of the remaining enigmas in thyroidology. Glucocorticoids (GCs) are strongly recommended but their effects are not completely satisfactory and adverse reactions can occur. Tripterygium glycosides (TG) is a promising… read more here.
Keywords: graves ophthalmopathy; efficacy safety; tripterygium; efficacy ... See more keywords
Novel observational study protocol to develop a prediction model that identifies patients with Graves’ ophthalmopathy insensitive to intravenous glucocorticoids pulse therapy
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DOI: 10.1136/bmjopen-2021-053173
Abstract: Introduction Intravenous glucocorticoids pulse therapy is the first-line treatment for moderate-to-severe and active Graves’ ophthalmopathy, with a large proportion of patients having poor efficacy and exposed to the risk of glucocorticoids adverse effects. We introduce… read more here.
Keywords: glucocorticoids pulse; intravenous glucocorticoids; pulse therapy; graves ophthalmopathy ... See more keywords
Value of Infrared Thermography Camera Attached to a Smartphone for Evaluation and Follow-up of Patients with Graves' Ophthalmopathy
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DOI: 10.1155/2019/7065713
Abstract: Purpose Graves' ophthalmopathy (GO) is the most common extra-thyroid manifestation of Graves' disease (GD). The Clinical Activity Score (CAS) has been widely used to evaluate GO inflammation severity and response to treatment; however, it is… read more here.
Keywords: graves ophthalmopathy; infrared thermography; upper eyelids; cas ... See more keywords
IRF7 Gene Variations Confer Susceptibility to Autoimmune Thyroid Diseases and Graves' Ophthalmopathy
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DOI: 10.1155/2019/7429187
Abstract: The objective of this study was to investigate whether IRF7 polymorphisms are associated with autoimmune thyroid diseases (AITDs). We selected three single nucleotide polymorphisms (SNPs) of IRF7, namely, rs1061501, rs1131665, and rs1061502 for genotyping using… read more here.
Keywords: graves ophthalmopathy; thyroid diseases; autoimmune thyroid; gene ... See more keywords
Analysis of Foveal and Parafoveal Microvascular Density and Retinal Vessel Caliber Alteration in Inactive Graves' Ophthalmopathy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ophthalmology"
DOI: 10.1155/2020/7643737
Abstract: Purpose We aimed to evaluate foveal and parafoveal density using optical coherence tomography angiography and the alteration on the retinal vessel diameter in patients with inactive Graves' ophthalmopathy compared to age-matched normal population. Materials and… read more here.
Keywords: graves ophthalmopathy; retinal vessel; foveal parafoveal; inactive graves ... See more keywords
Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves' Ophthalmopathy through the Regulation of FoxO3a Signaling
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DOI: 10.1155/2021/8888913
Abstract: Graves' ophthalmopathy (GO), which is characterized by orbital tissue inflammation, expansion, and fibrosis, is the ocular manifestation in 25% to 50% of patients with Graves' disease. As the pathology of GO is driven by autoimmune… read more here.
Keywords: graves ophthalmopathy; orbital fibroblasts; cyr61 expression; cultured orbital ... See more keywords