Antinociceptive Grayanane Diterpenoids from the Leaves of Pieris japonica.
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DOI: 10.1021/acs.jnatprod.9b00569
Abstract: Thirteen new grayanane diterpenoids (1-13) and 15 known analogues (14-28) were isolated from a leaf extract of Pieris japonica. Their structures were determined by spectrometric and spectroscopic methods, including HRESIMS, NMR, IR, and UV. The… read more here.
Keywords: pieris japonica; antinociceptive effects; grayanane diterpenoids; antinociceptive grayanane ... See more keywords
Enantioselective Total Syntheses of Grayanane Diterpenoids: (-)-Grayanotoxin III, (+)-Principinol E, and (-)-Rhodomollein XX.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01692
Abstract: Enantioselective total syntheses of (-)-grayanotoxin III, (+)-principinol E, and (-)-rhodomollein XX were accomplished based on a convergent strategy. The left- and right-wing fragments were assembled via the diastereoselective Mukaiyama aldol reaction catalyzed by a chiral… read more here.
Keywords: grayanane diterpenoids; principinol rhodomollein; total syntheses; grayanotoxin iii ... See more keywords
Divergent Synthetic Approach to Grayanane Diterpenoids.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.3c00753
Abstract: The total syntheses of nine grayanane diterpenoids, namely, GTX-II (1), GTX-III (2), rhodojaponin III (3), GTX-XV (4), principinol D (5), iso-GTX-II (6), 1,5-seco-GTX-Δ1,10-ene (7), and leucothols B (8) and D (9), that belong to five… read more here.
Keywords: grayanane diterpenoids; grayanane; divergent synthetic; synthetic approach ... See more keywords