An update of molecular findings in uterine tumor resembling ovarian sex cord tumor and GREB1‐rearranged uterine sarcoma with variable sex‐cord differentiation
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DOI: 10.1002/gcc.22909
Abstract: Uterine tumor resembling ovarian sex cord tumor (UTROSCT) is a uterine mesenchymal tumor defined histologically by showing sex cord‐like growth patterns, such as sheets, nests, trabeculae, cords, or tubules, with/without Sertoli‐like or Leydig‐like components, and… read more here.
Keywords: sex cord; sex; uterine tumor; greb1 ... See more keywords
GREB1 genetic variants are associated with bone mineral density in Caucasians
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DOI: 10.1007/s00774-017-0823-x
Abstract: Gaining an understanding of factors contributing to bone quality is key to the development of effective preventative treatments for osteoporosis and reduction in osteoporotic fractures. Oestrogen is a strong regulator of bone remodelling which maintains… read more here.
Keywords: greb1; significantly associated; bone mineral; mineral density ... See more keywords
GREB1 is an estrogen receptor-regulated tumour promoter that is frequently expressed in ovarian cancer
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DOI: 10.1038/s41388-018-0377-y
Abstract: Estrogenic hormone replacement therapy increases the risk of developing ovarian cancer, and estrogen promotes tumour initiation and growth in mouse models of this disease. GREB1 (Growth regulation by estrogen in breast cancer 1) is an… read more here.
Keywords: cancer; greb1; ovarian cancer; estrogen receptor ... See more keywords