A greedy classifier optimization strategy to assess ion channel blocking activity and pro-arrhythmia in hiPSC-cardiomyocytes
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DOI: 10.1371/journal.pcbi.1008203
Abstract: Novel studies conducting cardiac safety assessment using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are promising but might be limited by their specificity and predictivity. It is often challenging to correctly classify ion channel blockers or… read more here.
Keywords: optimization strategy; classifier optimization; ion channel; greedy classifier ... See more keywords