The identification of mediating effects using genome-based restricted maximum likelihood estimation
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DOI: 10.1371/journal.pgen.1010638
Abstract: Mediation analysis is commonly used to identify mechanisms and intermediate factors between causes and outcomes. Studies drawing on polygenic scores (PGSs) can readily employ traditional regression-based procedures to assess whether trait M mediates the relationship… read more here.
Keywords: based restricted; health; effect; genome based ... See more keywords