An autism-associated mutation in GluN2B prevents NMDA receptor trafficking and interferes with dendrite growth
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DOI: 10.1242/jcs.232892
Abstract: ABSTRACT Autism spectrum disorders (ASDs) are neurodevelopmental disorders with multiple genetic associations. Analysis of de novo mutations identified GRIN2B, which encodes the GluN2B subunit of NMDA receptors, as a gene linked to ASDs with high… read more here.
Keywords: glun2b; nmda receptor; autism; grin2b mutations ... See more keywords