Liquid Assisted Grinding for the N-Demethylation of Alkaloids
Sign Up to like & getrecommendations! Published in 2018 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.8b01393
Abstract: A mechanochemical approach has been demonstrated for the selective cleavage of nitrogen–carbon bonds in the N-demethylation of various alkaloids relevant in the pharmaceutical industry. This methodology employs a range of so-called “liquid additives” used in… read more here.
Keywords: liquid assisted; assisted grinding; grinding demethylation; demethylation alkaloids ... See more keywords