Molecular phylogeny and genetic diversity based on msp1a, groEL and gltA genes of Anaplasma ovis Tunisian isolates compared to available worldwide isolates and strains.
Sign Up to like & getrecommendations! Published in 2020 at "Ticks and tick-borne diseases"
DOI: 10.1016/j.ttbdis.2020.101447
Abstract: Anaplasma ovis, the causative agent of ovine anaplasmosis in tropical and subtropical countries, is a tick-borne obligatory intraerythrocytic bacterium of sheep, goats and wild ruminants. In Tunisia, data about the molecular phylogeny and the genetic… read more here.
Keywords: genetic diversity; phylogeny genetic; groel; molecular phylogeny ... See more keywords
Inhibition of Aβ1-42 fibrillation by chaperonins: human Hsp60 is a stronger inhibitor than its bacterial homologue GroEL.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00183
Abstract: Alzheimer's disease is a chronic neurodegenerative disease characterized by the accumulation of pathological aggregates of amyloid beta peptide. Many efforts have been focused on understanding peptide aggregation pathways and on identification of molecules able to… read more here.
Keywords: aggregation; human hsp60; groel; fibrillation chaperonins ... See more keywords
Protein chain collapse modulation and folding stimulation by GroEL-ES
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abl6293
Abstract: The collapse of polypeptides is thought important to protein folding, aggregation, intrinsic disorder, and phase separation. However, whether polypeptide collapse is modulated in cells to control protein states is unclear. Here, using integrated protein manipulation… read more here.
Keywords: groel; protein chain; chain collapse; collapse modulation ... See more keywords
In vivo client proteins of the chaperonin GroEL-GroES provide insight into the role of chaperones in protein evolution
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1091677
Abstract: Protein folding is often hampered by intermolecular protein aggregation, which can be prevented by a variety of chaperones in the cell. Bacterial chaperonin GroEL is a ring-shaped chaperone that forms complexes with its cochaperonin GroES,… read more here.
Keywords: client proteins; chaperonin groel; protein evolution; groel groes ... See more keywords
GroEL Chaperonin-Based Assay for Early Diagnosis of Scrub Typhus
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12010136
Abstract: A point-of-care diagnostic for early and rapid diagnosis of scrub typhus caused by Orientia tsutsugamushi is required for prompt and proper treatment of patients presenting with undifferentiated febrile illnesses. In this study, an immunochromatographic antigen… read more here.
Keywords: diagnosis; scrub typhus; typhus; groel ... See more keywords
Borrelia burgdorferi Surface Exposed GroEL Is a Multifunctional Protein
Sign Up to like & getrecommendations! Published in 2021 at "Pathogens"
DOI: 10.3390/pathogens10020226
Abstract: The spirochete, Borrelia burgdorferi, has a large number of membrane proteins involved in a complex life cycle, that includes a tick vector and a vertebrate host. Some of these proteins also serve different roles in… read more here.
Keywords: protein; surface exposed; exposed groel; groel ... See more keywords
groEL gene-based molecular detection and antibiogram profile of Riemerella anatipestifer from duck in Bangladesh
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Advanced Veterinary and Animal Research"
DOI: 10.5455/javar.2022.i637
Abstract: Objectives: This study was designed to detect Riemerella anatipestifer through polymerase chain reaction (PCR) from duck farming areas of the Mymensingh and Sylhet divisions and to determine the antibiogram profile of the PCR-positive isolates using… read more here.
Keywords: duck; antibiogram profile; riemerella anatipestifer; gene ... See more keywords