Functional-Group-Directed Regiodivergent (3 + 2) Annulations of Electronically Distinct 1,3-Dienes and 2-Formyl Arylboronic Acids.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c00160
Abstract: Presented herein is a palladium-catalyzed asymmetric (3 + 2) annulation reaction between 1,3-dienes and 2-formylarylboronic acids, proceeding in a cascade vinylogous addition and Suzuki coupling process. Both electron-neutral and electron-deficient 1,3-dienes are compatible under similar… read more here.
Keywords: annulations electronically; functional group; group directed; group ... See more keywords
Amide-Group-Directed Protonolysis of Cyclopropane: An Approach to 2,2-Disubstituted Pyrrolidines.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b00584
Abstract: Regioselective protonolytic C-C bond cleavage of acylated aminomethyl cyclopropanes can be achieved using trifluoroacetic acid. The intermediate tertiary carbenium ion undergoes an intramolecular amination to give 2,2-substituted pyrrolidines. The strength of the acid and the… read more here.
Keywords: directed protonolysis; approach disubstituted; cyclopropane approach; amide group ... See more keywords
1,3,5-Triazine group directed Rh(III)-catalyzed C-H alkylation of indoles with maleimides
Sign Up to like & getrecommendations! Published in 2025 at "New Journal of Chemistry"
DOI: 10.1039/d4nj04518a
Abstract: A Rhodium(III)-catalyzed C2-selective C-H activation of indoles bearing a 1,3,5-triazine directing group (DG) and conjugated addition to maleimides under air has been described, furnishing the corresponding products in up to... read more here.
Keywords: group directed; group; triazine group; catalyzed alkylation ... See more keywords