Transient Directing Group Enabled Pd-catalyzed γ-C(sp3)-H Oxygenation of Alkyl Amines.
Sign Up to like & getrecommendations! Published in 2020 at "ACS catalysis"
DOI: 10.1021/acscatal.0c01310
Abstract: We report a general protocol for γ-C(sp3)-H acyloxylation and alkoxylation of free amines using 2-hydroxynicotinaldehyde as the transient directing group. In the presence of an electrophilic fluorinating bystanding oxidant and acetic acid, a wide range… read more here.
Keywords: directing group; catalyzed sp3; group enabled; transient directing ... See more keywords
Transient directing group enabled Pd-catalyzed C–H oxygenation of benzaldehydes and benzylic amines
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra00241h
Abstract: We report a general protocol for ortho-C–H fluoroalkoxylation of benzaldehydes and benzylic amines utilizing an inexpensive amino amide as a transient directing group. In the presence of an electrophilic fluorinating bystanding oxidant and fluorinated alcohols,… read more here.
Keywords: transient directing; benzaldehydes benzylic; benzylic amines; group enabled ... See more keywords