High levels of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine accumulate in the brain tissues of xeroderma pigmentosum group A gene-knockout mice.
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DOI: 10.1016/j.dnarep.2019.04.004
Abstract: Xeroderma pigmentosum (XP) is a genetic disorder associated with defects in nucleotide excision repair, a pathway that eliminates a wide variety of helix-distorting DNA lesions, including ultraviolet-induced pyrimidine dimers. In addition to skin diseases in… read more here.
Keywords: oxidatively generated; group gene; cyclo; xeroderma pigmentosum ... See more keywords