Iridium-Catalyzed C-Alkylation of Methyl Group on N-Heteroaromatic Compounds using Alcohols.
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DOI: 10.1021/acs.orglett.0c02635
Abstract: In this study, we developed a catalytic system for the C-alkylation of a methyl group on N-heteroaromatic compounds, including pyridine, pyrimidine, pyrazine, quinoline, quinoxaline, and isoquinoline, using alcohols based on a hydrogen-borrowing process with [Cp*IrCl2]2… read more here.
Keywords: group heteroaromatic; methyl group; heteroaromatic compounds; alkylation methyl ... See more keywords