Group IIA secreted phospholipase A2 controls skin carcinogenesis and psoriasis by shaping the gut microbiota
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DOI: 10.1172/jci.insight.152611
Abstract: Besides promoting inflammation by mobilizing lipid mediators, group IIA secreted phospholipase A2 (sPLA2-IIA) prevents bacterial infection by degrading bacterial membranes. Here, we show that, despite the restricted intestinal expression of sPLA2-IIA in BALB/c mice, its… read more here.
Keywords: gut microbiota; iia; spla2 iia; group iia ... See more keywords
Inhibitory Effect of Zingerone on Secretory Group IIA Phospholipase A2
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DOI: 10.1177/1934578x1701200624
Abstract: The expression of secretory group IIA phospholipase A2 (sPLA2-IIA) has been shown to be elevated in various inflammatory diseases, and lipopolysaccharide (LPS) up-regulates the expression of sPLA2-IIA in human umbilical vein endothelial cells (HUVECs). Zingerone… read more here.
Keywords: group iia; expression; iia phospholipase; secretory group ... See more keywords
Inhibitory Effect of Pelargonidin on Secretory Group IIA Phospholipase A2
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DOI: 10.1177/1934578x1801300811
Abstract: The expression of secretory group IIA phospholipase A2 (sPLA2-IIA) has been shown to be elevated in various inflammatory diseases, and lipopolysaccharide (LPS) up-regulates the expression of sPLA2-IIA in human umbilical vein endothelial cells (HUVECs). Pelargonidin… read more here.
Keywords: group iia; expression; iia phospholipase; secretory group ... See more keywords
Effects of Statins and Xuezhikang on the Expression of Secretory Phospholipase A2, Group IIA in Rat Vascular Smooth Muscle Cells.
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DOI: 10.1536/ihj.16-163
Abstract: Atherosclerosis is a multifactorial vascular disease characterized by formation of inflammatory lesions. Secretory phospholipase A2, group IIA (sPLA2-IIA) is involved in this process and plays a critical role. However, the exact role of sPLA2-IIA in… read more here.
Keywords: phospholipase group; group iia; expression; secretory phospholipase ... See more keywords
Multimodal regulation of the osteoclastogenesis process by secreted group IIA phospholipase A2
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.966950
Abstract: Increasing evidence points to the involvement of group IIA secreted phospholipase A2 (sPLA2-IIA) in pathologies characterized by abnormal osteoclast bone-resorption activity. Here, the role of this moonlighting protein has been deepened in the osteoclastogenesis process… read more here.
Keywords: osteoclastogenesis process; group iia; spla2 iia; iia ... See more keywords