Model-based Investigation of Inadequate Efficacy of Tesnatilimab, an Anti- Natural Killer Group 2 Member D (NKG2D) Monoclonal Antibody, in Moderately to Severely Active Crohn's Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2252
Abstract: Tesnatilimab is a human immunoglobulin G4 isotype monoclonal antibody that blocks the natural killer group 2 member D (NKG2D) receptor and prevent the downstream signaling of proinflammatory cytokines and cytotoxic mediators. Subcutaneous tesnatilimab was investigated… read more here.
Keywords: monoclonal antibody; killer group; natural killer; group member ... See more keywords
The codevelopment of group relationships: The role of individual group member's and other group members' mutual influence and shared group environment.
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DOI: 10.1037/cou0000349
Abstract: Although recent research has provided empirical support for the codevelopment of group interaction (defined as development in a common direction of perceptions of group relationships), no studies have yet investigated the "causes" of codevelopment among… read more here.
Keywords: group relationships; group; influence; group members ... See more keywords
Bonobos assign meaning to food calls based on caller food preferences
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DOI: 10.1371/journal.pone.0267574
Abstract: Human communication relies heavily on pragmatic competence. Speech utterances are often ambiguous requiring listeners to use interaction history, shared knowledge, presumed intention and other contextual variables to make inferences about a speaker’s meaning. To probe… read more here.
Keywords: food; food calls; group member; group ... See more keywords
More than Decoration: Roles for Natural Killer Group 2 Member D Ligand Expression by Immune Cells
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DOI: 10.3389/fimmu.2018.00231
Abstract: The activating immune receptor natural killer group 2 member D (NKG2D), which is expressed by natural killer cells and T cell subsets, recognizes a number of ligands expressed by “stressed” or damaged cells. NKG2D has… read more here.
Keywords: nkg2d ligands; natural killer; expression; killer group ... See more keywords
New Insights Into the Regulation of Natural-Killer Group 2 Member D (NKG2D) and NKG2D-Ligands: Endoplasmic Reticulum Stress and CEA-Related Cell Adhesion Molecule 1
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01324
Abstract: Natural-killer group 2 member D (NKG2D) is a well-characterized activating receptor expressed by natural killer (NK) cells, NKT cells, activated CD8+ T cells, subsets of γδ+ T cells, and innate-like T cells. NKG2D recognizes multiple… read more here.
Keywords: nkg2d ligands; natural killer; stress; killer group ... See more keywords
In- and Out-Group Effects on Social Perception and Empathy in Cocaine Use Disorder
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DOI: 10.3389/fpsyt.2022.879016
Abstract: Earlier research revealed that cocaine users display impairments in emotional but not necessarily in cognitive empathy. However, no study to date has tested whether empathy is generally altered or whether impairments are restricted to specific… read more here.
Keywords: cocaine user; group member; group; cocaine ... See more keywords