Mechanisms and functional impact of Group I metabotropic glutamate receptor modulation of excitability in mouse MNTB neurons
Sign Up to like & getrecommendations! Published in 2019 at "Synapse"
DOI: 10.1002/syn.22137
Abstract: We examined effects of Group I metabotropic glutamate receptors on the excitability of mouse medial nucleus of the trapezoid body (MNTB) neurons. The selective agonist, S‐3,5‐dihydroxyphenylglycine (DHPG), evoked a dose‐dependent depolarization of the resting potential,… read more here.
Keywords: metabotropic glutamate; group; excitability mouse; mntb neurons ... See more keywords
Control of neuronal excitability by Group I metabotropic glutamate receptors
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Reviews"
DOI: 10.1007/s12551-017-0301-7
Abstract: Metabotropic glutamate (mGlu) receptors couple through G proteins to regulate a large number of cell functions. Eight mGlu receptor isoforms have been cloned and classified into three Groups based on sequence, signal transduction mechanisms and… read more here.
Keywords: glutamate receptors; metabotropic glutamate; group metabotropic; metabotropic ... See more keywords
Group II metabotropic glutamate receptor activation in the basolateral amygdala mediates individual differences in stress-induced changes in rapid eye movement sleep
Sign Up to like & getrecommendations! Published in 2021 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2020.110014
Abstract: Group II metabotropic glutamate receptors (mGluR2/3 s) have been implicated in stress and trauma related disorders including post-traumatic stress disorder (PTSD). PTSD is characterized by flashbacks, anxiety, and sleep disturbances. While many people are exposed to… read more here.
Keywords: individual differences; metabotropic glutamate; differences stress; stress ... See more keywords
Group II Metabotropic Glutamate Receptor (mGlu2 and mGlu3) Roles in Thalamic Processing.
Sign Up to like & getrecommendations! Published in 2021 at "British journal of pharmacology"
DOI: 10.1111/bph.15640
Abstract: BACKGROUND AND PURPOSE As the thalamus underpins almost all aspects of behaviour, it is important to understand how the thalamus operates. Group II metabotropic glutamate (mGlu2/mGlu3) receptor activation reduces inhibition in thalamic nuclei originating from… read more here.
Keywords: receptor; mglu3; metabotropic glutamate; group metabotropic ... See more keywords
Phosphorylation and regulation of group II metabotropic glutamate receptors (mGlu2/3) in neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1022544
Abstract: Group II metabotropic glutamate (mGlu) receptors (mGlu2/3) are Gαi/o-coupled receptors and are primarily located on presynaptic axonal terminals in the central nervous system. Like ionotropic glutamate receptors, group II mGlu receptors are subject to regulation… read more here.
Keywords: group; metabotropic glutamate; group metabotropic; regulation ... See more keywords
Group I Metabotropic Glutamate Receptors Modulate Motility and Enteric Neural Activity in the Mouse Colon
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13010139
Abstract: Glutamate is the major excitatory neurotransmitter in the central nervous system, and there is evidence that Group-I metabotropic glutamate receptors (mGlu1 and mGlu5) have established roles in excitatory neurotransmission and synaptic plasticity. While glutamate is… read more here.
Keywords: glutamate; group; metabotropic glutamate; glutamate receptors ... See more keywords
Group I Metabotropic Glutamate Receptors and Interacting Partners: An Update
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020840
Abstract: Group I metabotropic glutamate (mGlu) receptors (mGlu1/5 subtypes) are G protein-coupled receptors and are broadly expressed in the mammalian brain. These receptors play key roles in the modulation of normal glutamatergic transmission and synaptic plasticity,… read more here.
Keywords: group; metabotropic glutamate; interacting partners; group metabotropic ... See more keywords