Antidepressant Effects and Mechanisms of Group II mGlu Receptor-Specific Negative Allosteric Modulators
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DOI: 10.1016/j.neuron.2019.12.011
Abstract: In this issue of Neuron, Joffe et al. (2020) assess the antidepressant-relevant effects and underlying neural mechanisms of negative allosteric modulators selective for either metabotropic glutamate receptors 2 (mGlu2) or 3 (mGlu3). Negative modulation of both… read more here.
Keywords: mechanisms group; effects mechanisms; negative allosteric; allosteric modulators ... See more keywords
Acid‐sensing ion channel 1a is required for mGlu receptor dependent long‐term depression in the hippocampus
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DOI: 10.1016/j.phrs.2017.01.028
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Acid‐sensing ion channels (ASICs), members of the degenerin/epithelial Na+ channel superfamily, are widely distributed in the mammalian nervous system. ASIC1a is highly permeable to Ca2+ and are thought… read more here.
Keywords: sensing ion; mglu receptor; receptor; group mglu ... See more keywords