Methotrexate-induced toxic effects and the ameliorating effects of astaxanthin on genitourinary tissues in a female rat model
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-021-06000-2
Abstract: The purpose of the study was to explore the possible deleterious effects of Methotrexate (MTX) treatment on the urogenital tissues and the potential protective effects of Astaxanthin (AXA). Twenty-four female Wistar Albino rats (12 months… read more here.
Keywords: rats received; group rats; compared group; group ... See more keywords
A Multimodal MR Imaging Study of the Effect of Hippocampal Damage on Affective and Cognitive Functions in a Rat Model of Chronic Exposure to a Plateau Environment
Sign Up to like & getrecommendations! Published in 2022 at "Neurochemical Research"
DOI: 10.1007/s11064-021-03498-5
Abstract: Prolonged exposure to high altitudes above 2500 m above sea level (a.s.l.) can cause cognitive and behavioral dysfunctions. Herein, we sought to investigate the effects of chronic exposure to plateau hypoxia on the hippocampus in a… read more here.
Keywords: plateau; group; group rats; chronic exposure ... See more keywords
Alleviative effect of licorice on copper chloride-induced oxidative stress in the brain: biochemical, histopathological, immunohistochemical, and genotoxic study
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-017-9503-6
Abstract: Although copper is an essential micronutrient involved in a variety of biological processes indispensable for sustaining life, it can be toxic when administered in excess. Licorice (Glycyrrhizaglabra) has been used in Chinese folk medicine for… read more here.
Keywords: licorice; group rats; brain; copper chloride ... See more keywords
Effects of a Chinese herbal extract on the intestinal tract and aquaporin in Adriamycin-induced nephropathy
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2014620
Abstract: ABSTRACT Wuling Decoction is a traditional Chinese medicine that has been used to open knots, benefit water, transform Qi, return fluid, and has a significant effect on strengthening the spleen and removing dampness. To explore… read more here.
Keywords: group rats; water; wuling decoction; group ... See more keywords
Role of the p38MAPK signaling pathway in hippocampal neuron autophagy in rats with chronic intermittent hypoxia.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neurophysiology"
DOI: 10.1152/jn.00240.2021
Abstract: This study explored the role of the p38 mitogen-activated protein kinase (MAPK) signaling pathway in hippocampal neuron autophagy in rats with chronic intermittent hypoxia (CIH). Sixty-four male Sprague-Dawley rats were randomly divided to normoxic control… read more here.
Keywords: hypoxia; group rats; group; cih veh ... See more keywords
Changes in gene expression and neuroinflammation in the hippocampus of rats with poststroke cognitive impairment.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental biology and medicine"
DOI: 10.1177/15353702231157922
Abstract: Poststroke cognitive impairment (PSCI) often occurs during the stroke recovery period and greatly increases the difficulty of rehabilitation. Activation of neuroinflammation and long-term changes in gene expression patterns in the hippocampus could be essential in… read more here.
Keywords: group rats; expression; changes gene; hippocampus ... See more keywords
Study of the protective effects of cyanocobalamin on methotrexate induced nephrotoxicity in rats
Sign Up to like & getrecommendations! Published in 2022 at "F1000Research"
DOI: 10.12688/f1000research.124081.2
Abstract: Background: Methotrexate (MTX) is a chemotherapeutic drug, used mainly in many cancerous stages, inflammatory and auto-immune diseases, but its use has been limited by its nephrotoxicity. Cyanocobalamin is a water-soluble vitamin possessing nephro-protective properties. The… read more here.
Keywords: cyanocobalamin; day; group rats; methotrexate ... See more keywords