Low concentrations of sodium arsenite induce hepatotoxicity in prepubertal male rats
Sign Up to like & getrecommendations! Published in 2019 at "Environmental Toxicology"
DOI: 10.1002/tox.22890
Abstract: Arsenic (As) can contaminate air, soil, water, and organisms through mobilization of natural mineralogical deposits or anthropogenic actions. Inorganic‐As compounds are more toxic and widely available in aquatic environments, including drinking water reservoir catchments. Since… read more here.
Keywords: concentrations sodium; water; sodium arsenite; arsenite induce ... See more keywords
In vivo assessment of the drug interaction between sorafenib and paracetamol in rats
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-020-04075-3
Abstract: Purpose Sorafenib is a multi-targeted tyrosine kinase inhibitor (TKI) used for the treatment of advanced renal cell carcinoma, hepatocellular carcinoma and radioactive iodine resistant thyroid carcinoma. Neoplastic diseases are the cause of pain, which may… read more here.
Keywords: drug; group received; paracetamol; sorafenib paracetamol ... See more keywords
Is there any effect of montelukast on prevention of myringosclerosis after myringotomy in a rat model?
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5181-3
Abstract: ObjectivesIn this study, our aim was to identify the possible effects of montelukast sodium (ML) on the prevention of experimentally induced myringosclerosis.Materials and methodsTwenty-eight female Wistar albino rats were used and they were divided into… read more here.
Keywords: montelukast prevention; group; myringosclerosis; effect montelukast ... See more keywords
Fucoidan alleviates microcystin-LR-induced hepatic, renal, and cardiac oxidative stress and inflammatory injuries in mice
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DOI: 10.1007/s11356-019-06931-z
Abstract: Fucoidans (FUCs) are sulfated polysaccharides that have a wide range of bioactivities. The current study was designed to evaluate the antioxidant potential of FUC against microcystin-LR (MC-LR)-induced toxicity. Five mice groups ( n = 8) were… read more here.
Keywords: hepatic renal; renal cardiac; microcystin induced; group ... See more keywords
Bendiocarb-induced nephrotoxicity in rats and the protective role of vitamins C and E
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DOI: 10.1007/s11356-019-07260-x
Abstract: Bendiocarb is a pesticide carbamate which is used to protect agricultural products and animals. In this study, rats were given orally with bendiocarb and also other chemicals via gavage. Male rats were randomly divided into… read more here.
Keywords: induced nephrotoxicity; bendiocarb vitamin; bendiocarb induced; group ... See more keywords
Coenzyme Q10 Cardioprotective Effects Against Doxorubicin-Induced Cardiotoxicity in Wistar Rat
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular Toxicology"
DOI: 10.1007/s12012-019-09547-4
Abstract: In the present study, we investigated the cardioprotective effects of coenzyme Q10 (Q10) against doxorubicin (DOXO) induced cardiomyopathy. Twenty adult rats were distributed in four experimental groups: group 1 received NaCl 0.9% at 1 ml/day for… read more here.
Keywords: heart; cardioprotective effects; doxo; treatment ... See more keywords
Therapeutic potential of selenium in letrozole induced polycystic ovary syndrome rat model: Targeting mitochondrial approach.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.06.009
Abstract: Polycystic ovary syndrome (PCOS) is the most common endorinopathy in fertile women with heterogeneous reproductive and metabolic phenotypes and unknown etiology. This study was undertaken to investigate the beneficial effect of selenium in management of… read more here.
Keywords: polycystic ovary; pcos; letrozole induced; ovary syndrome ... See more keywords
Protective effect of gallic acid against cisplatin-induced ototoxicity in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Brazilian journal of otorhinolaryngology"
DOI: 10.1016/j.bjorl.2018.03.001
Abstract: INTRODUCTION Cisplatin is an antineoplastic agent widely used in the treatment of a variety of cancers. Ototoxicity is one of the main side-effects restricting the use of cisplatin. OBJECTIVE The purpose of this study was… read more here.
Keywords: gallic acid; cisplatin; ototoxicity; acid ... See more keywords
Synergistic use of florfenicol and Salvia miltiorrhiza polysaccharide can enhance immune responses in broilers.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.111825
Abstract: To explore the effect of florfenicol (FFC) combined with Salvia miltiorrhiza polysaccharide (SMPs) on immune function of Broilers. One hundred and twenty-one-day-old chicks were chosen and divided into 6 groups. The group A received standard… read more here.
Keywords: synergistic use; enhance immune; basal diet; salvia miltiorrhiza ... See more keywords
The potential role of pomegranate and its nano-formulations on cerebral neurons in aluminum chloride induced Alzheimer rat model
Sign Up to like & getrecommendations! Published in 2020 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2020.04.045
Abstract: The oxidative stress leading to degenerative changes in the brain of Alzheimer’s disease (AD) is evident. Our aim was to evaluate the therapeutic and protective effects of pomegranate extract (PE) and pomegranate extract-loaded nanoparticles (PE… read more here.
Keywords: model; rat model; weeks group; group received ... See more keywords
Naringenin blocks hepatic cadmium accumulation and suppresses cadmium-induced hepatotoxicity via amelioration of oxidative inflammatory signaling and apoptosis in rats.
Sign Up to like & getrecommendations! Published in 2023 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2023.2196377
Abstract: Liver is one of the targets of cadmium (Cd) bioaccumulation for hepatic damage and pathologies via oxidative inflammation and apoptosis. The current study explored whether the citrus flavonoid naringenin (NAR) could prevent hepatic accumulation of… read more here.
Keywords: apoptosis; group received; cadmium; accumulation ... See more keywords