Group A rotaviruses circulating prior to a national immunization programme in Nigeria: Clinical manifestations, high G12P[8] frequency, intra‐genotypic divergence of VP4 and VP7
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DOI: 10.1002/jmv.24949
Abstract: Nigeria having approximately 50 000 Rotavirus A (RVA) deaths annually is yet to introduce RVA vaccine into routine national immunization; therefore surveillance of RVA strains circulating before vaccine introduction is essential in evaluating impact of the… read more here.
Keywords: national immunization; vp7; rva; group rotaviruses ... See more keywords
Host Serine Proteases TMPRSS2 and TMPRSS11D Mediate Proteolytic Activation and Trypsin-Independent Infection in Group A Rotaviruses
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DOI: 10.1128/jvi.00398-21
Abstract: Proteolytic cleavage of the viral VP4 protein is essential for virion maturation and infectivity in group A rotaviruses (RVAs). In cell culture, RVAs are propagated in culture medium supplemented with the exogenous protease trypsin, which… read more here.
Keywords: activation; group rotaviruses; infection; tmprss2 tmprss11d ... See more keywords
Cytotoxic effect of unclassified group K rotaviruses on T98G and U87MG glioblastoma cells in vitro.
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DOI: 10.1200/jco.2020.38.15_suppl.e15597
Abstract: e15597Background: Oncolytic virotherapy is developing intensively in modern oncology. Viruses demonstrate the ability to the direct oncolysis and to the stimulation of antitumor immune activity; th... read more here.
Keywords: unclassified group; effect unclassified; cytotoxic effect; group rotaviruses ... See more keywords
Detection of nongroup A rotaviruses in faecal samples of pigs in the Czech Republic
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DOI: 10.17221/3081-vetmed
Abstract: Besides group A rotaviruses, group B and C rotaviruses have been detected as the cause of diarrheal diseases in pigs. Of a set of 329 faecal samples from pigs, 16 samples were selected in which… read more here.
Keywords: detection; faecal samples; group; group rotaviruses ... See more keywords