Long-term Risk of Epilepsy Following Invasive Group B Streptococcus Disease in Neonates in Denmark
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.9507
Abstract: Key Points Question Is neonatal invasive Group B Streptococcus (iGBS) sepsis or meningitis associated with increased risk of epilepsy? Findings This cohort study of children born in Denmark from 1997 through 2017 found children diagnosed… read more here.
Keywords: invasive group; risk; risk epilepsy; group streptococcus ... See more keywords
Application of Fmoc-SPPS, Thiol-Maleimide Conjugation, and Copper(I)-Catalyzed Alkyne-Azide Cycloaddition "Click" Reaction in the Synthesis of a Complex Peptide-Based Vaccine Candidate Against Group A Streptococcus.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0227-0_2
Abstract: Fmoc solid-phase peptide synthesis (SPPS) is the most common approach used to synthesize natural and unnatural peptides. However, the synthesis of sequences longer than 30-60 amino acids is associated with a drastic reduction in peptide… read more here.
Keywords: candidate group; group streptococcus; vaccine candidate; fmoc spps ... See more keywords
A Mouse Nasopharyngeal Colonization Model for Group A Streptococcus.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_23
Abstract: Group A Streptococcus (GAS) often exists as an asymptomatic colonizer of the upper respiratory tract in humans. Unsurprisingly, a high proportion of symptomatic infections caused by GAS include pharyngitis. While not usually life-threatening, these infections… read more here.
Keywords: nasopharyngeal colonization; colonization; model; group streptococcus ... See more keywords
Humanized Plasminogen Mouse Model to Study Group A Streptococcus Invasive Disease.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_24
Abstract: This chapter presents the methodology to carry out infection of humanized plasminogen mice with Group A Streptococcus (GAS). This model of invasive disease has been widely used within the field to study the virulence of… read more here.
Keywords: invasive disease; model; group streptococcus; humanized plasminogen ... See more keywords
Engineering of Group A Streptococcus Isopeptide Bonds into Immunoglobulin-Like Protein Domains.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_30
Abstract: Intramolecular isopeptide bonds, formed autocatalytically between Lys and Asn/Asp side chains, are widely present in the immunoglobulin-like domains of Gram-positive bacterial adhesins, including Group A Streptococcus, and confer considerable mechanical and chemical stability. These properties… read more here.
Keywords: isopeptide bonds; group streptococcus; engineering group; immunoglobulin like ... See more keywords
Genetic Manipulation of Group A Streptococcus-Gene Deletion by Allelic Replacement.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_5
Abstract: Genetic manipulation of Streptococcus pyogenes (Group A Streptococcus, GAS) has historically been a challenging process, with considerable variation in efficiency between different strains. Here, we outline an optimized, rapid method for creating markerless isogenic mutations… read more here.
Keywords: manipulation group; group streptococcus; streptococcus gene; genetic manipulation ... See more keywords
Group A Streptococcus Transcriptome Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_8
Abstract: Global gene expression analyses in bacteria have undergone a dramatic transformation. Prior to the development of high-throughput sequencing technologies, real-time PCR or microarray studies were the mainstay of assessing differences in gene expression in bacteria.… read more here.
Keywords: analysis; group streptococcus; streptococcus transcriptome; gene expression ... See more keywords
Survival of an emerging foodborne pathogen: Group B Streptococcus (GBS) serotype III sequence type (ST) 283—under simulated partial cooking and gastric fluid conditions
Sign Up to like & getrecommendations! Published in 2018 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-018-0525-8
Abstract: Group B Streptococcus (GBS) was previously not known to be transmitted through food, but an outbreak investigation in Singapore in 2015 documented for the first time an association between GBS Type III Sequence Type 283… read more here.
Keywords: type 283; streptococcus gbs; group streptococcus; iii sequence ... See more keywords
Group B Streptococcus chimeric capsular polysaccharides as novel multivalent vaccine candidates
Sign Up to like & getrecommendations! Published in 2021 at "Glycoconjugate Journal"
DOI: 10.1007/s10719-021-10000-4
Abstract: The capsular polysaccharide of the human pathogen Group B Streptococcus is a key virulence factor and vaccine candidate that induces protective antibodies when conjugated to carrier proteins. It consists of long polymeric chains of oligosaccharide… read more here.
Keywords: chimeric capsular; group streptococcus; group; capsular polysaccharides ... See more keywords
Polyglutamic acid-trimethyl chitosan-based intranasal peptide nano-vaccine induces potent immune responses against group A streptococcus.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.09.037
Abstract: Peptide-based vaccines have the potential to overcome the limitations of classical vaccines; however, their use is hampered by a lack of carriers and adjuvants suitable for human use. In this study, an efficient self-adjuvanting peptide… read more here.
Keywords: trimethyl chitosan; delivery; antigen; group streptococcus ... See more keywords
Duration of Group A Streptococcus PCR positivity following antibiotic treatment of pharyngitis.
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.10.003
Abstract: BACKGROUND Polymerase chain reaction (PCR) has high sensitivity and specificity for detection of group A streptococcus (GAS) in throat swabs and is routinely used for GAS pharyngitis diagnosis at our institution. Herein we defined the… read more here.
Keywords: gas pharyngitis; treatment; pharyngitis; group streptococcus ... See more keywords