Growth of B Cell Receptor Microclusters Is Regulated by PIP2 and PIP3 Equilibrium and Dock2 Recruitment and Activation.
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DOI: 10.1016/j.celrep.2017.10.117
Abstract: The growth of B cell receptor (BCR) microclusters upon antigen stimulation drives B cell activation. Here, we show that PI3K-mediated PIP3 production is required for the growth of BCR microclusters. This growth is likely inhibited… read more here.
Keywords: bcr; dock2; cell receptor; growth cell ... See more keywords