PPARα agonist alleviates tumor growth and chemo-resistance associated with the inhibition of glucose metabolic pathway.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172664
Abstract: As a nuclear receptor, peroxisome-proliferator-activated receptor α (PPARα) plays a critical role in regulation of metabolism and cancer, while the effect of PPARα agonist on cancer cell glucose metabolism-linked tumor growth is still unclear. Here… read more here.
Keywords: ppar agonist; growth chemo; cancer; wy14 643 ... See more keywords
CD44 variant 6 is associated with prostate cancer growth and chemo-/radiotherapy response in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.111850
Abstract: We have previously demonstrated that CD44 variant 6 (CD44v6) is associated with prostate cancer (CaP) growth and therapeutic resistance in vitro, however, the role of CD44v6 in CaP in vivo is not fully understood. The… read more here.
Keywords: radiotherapy response; cd44v6; growth chemo; chemo radiotherapy ... See more keywords