Arginyltransferase ATE1 is targeted to the neuronal growth cones and regulates neurite outgrowth during brain development
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.08.027
Abstract: Arginylation is an emerging protein modification mediated by arginyltransferase ATE1, shown to regulate embryogenesis and actin cytoskeleton, however its functions in different physiological systems are not well understood. Here we analyzed the role of ATE1… read more here.
Keywords: growth cones; brain; neurite outgrowth; ate1 ... See more keywords
Live Imaging of Cytoskeletal Dynamics in Embryonic Xenopus laevis Growth Cones and Neural Crest Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cold Spring Harbor protocols"
DOI: 10.1101/pdb.prot104463
Abstract: The cytoskeleton is a dynamic, fundamental network that not only provides mechanical strength to maintain a cell's shape but also controls critical events like cell division, polarity, and movement. Thus, how the cytoskeleton is organized… read more here.
Keywords: cones neural; growth cones; cytoskeletal dynamics; neural crest ... See more keywords
Förster resonance energy transfer efficiency of the vinculin tension sensor in cultured primary cortical neuronal growth cones
Sign Up to like & getrecommendations! Published in 2022 at "Neurophotonics"
DOI: 10.1117/1.nph.9.2.025002
Abstract: Abstract. Significance: Interaction of neurons with their extracellular environment and the mechanical forces at focal adhesions and synaptic junctions play important roles in neuronal development. Aim: To advance studies of mechanotransduction, we demonstrate the use… read more here.
Keywords: growth cones; fret efficiency; tension; vinculin ... See more keywords
Cue-Polarized Transport of β-actin mRNA Depends on 3′UTR and Microtubules in Live Growth Cones
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00300
Abstract: Guidance cues trigger fast responses in axonal growth cones such as directional turning and collapse that require local protein synthesis. An attractive cue-gradient, such as Netrin-1, triggers de novo synthesis of β-actin localized to the… read more here.
Keywords: actin mrna; growth cones; cue; growth ... See more keywords
Frataxin Deficit Leads to Reduced Dynamics of Growth Cones in Dorsal Root Ganglia Neurons of Friedreich’s Ataxia YG8sR Model: A Multilinear Algebra Approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.912780
Abstract: Computational techniques for analyzing biological images offer a great potential to enhance our knowledge of the biological processes underlying disorders of the nervous system. Friedreich’s Ataxia (FRDA) is a rare progressive neurodegenerative inherited disorder caused… read more here.
Keywords: growth cones; growth; frataxin; dynamics growth ... See more keywords