Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2424
Abstract: Elevated concentrations of growth differentiation factor 15 (GDF‐15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF‐15 concentrations represent remains unclear. Here, we aim… read more here.
Keywords: heart failure; differentiation factor; growth differentiation; patients heart ... See more keywords
Plasma growth differentiation factor‐15 in patients with “lone” atrial fibrillation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24373
Abstract: Growth differentiation factor‐15 (GDF‐15) is a member of the transforming growth factor β superfamily, correlated with various stimuli, including cardiovascular disease. The association between plasma GDF‐15 level and “lone” AF, that is, AF of unknown… read more here.
Keywords: growth; differentiation factor; growth differentiation; factor ... See more keywords
Low plasma growth/differentiation factor 1 levels are associated with liver fibrosis in patients with stable angina
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24745
Abstract: Growth differentiation factor 1 (GDF1) is a member of the transforming growth factor‐β (TGF‐β) superfamily and a protective mediator against the development of post‐infarction cardiac remodeling by negatively regulating MEK‐ERK1/2 and Smad signaling pathways in… read more here.
Keywords: differentiation factor; fibrosis; liver fibrosis; growth differentiation ... See more keywords
Associations of device‐measured sleep, sedentariness and physical activity with growth differentiation factor 15 in older adults
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12924
Abstract: Growth differentiation factor 15 (GDF‐15) is a biomarker for chronic disease burden that might explain the health effects of sedentary behaviours (SBs) and physical activity (PA). We examined associations of device‐measured sleep, SB and PA,… read more here.
Keywords: differentiation factor; growth differentiation; physical activity; associations device ... See more keywords
A new diagnostic indication device of a biomarker growth differentiation factor 15 for mitochondrial diseases: From laboratory to automated inspection
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12317
Abstract: Mitochondrial diseases (MDs) are occasionally difficult to diagnose. Growth differentiation factor 15 (GDF15) has been reported as a biomarker useful for not only diagnosing MDs, but also evaluating disease severity and therapeutic efficacy. To enable… read more here.
Keywords: ltia device; mitochondrial diseases; healthy controls; disease ... See more keywords
A peroxiredoxin‐based proteinaceous scaffold for the growth and differentiation of neuronal cells and tumour stem cells in the absence of prodifferentiation agents
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2144
Abstract: The use of nanoscale materials in the design of scaffolds for CNS tissue is increasing, due to their ability to promote cell adhesion, to mimic an extracellular matrix microenvironment and to interact with neuronal membranes.… read more here.
Keywords: growth differentiation; stem cells; differentiation; prodifferentiation ... See more keywords
Unidirectional neuronal cell growth and differentiation on aligned polyhydroxyalkanoate blend microfibres with varying diameters
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2911
Abstract: Polyhydroxyalkanoates (PHAs) are a family of prokaryotic‐derived biodegradable and biocompatible natural polymers known to exhibit neuroregenerative properties. In this work, poly(3‐hydroxybutyrate), P(3HB), and poly(3‐hydroxyoctanoate), P(3HO), have been combined to form blend fibres for directional guidance… read more here.
Keywords: neuronal cell; blend; differentiation; growth differentiation ... See more keywords
Associations Between Plasma Growth and Differentiation Factor-15 with Aging Phenotypes in Muscle, Adipose Tissue, and Bone.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-021-00912-6
Abstract: Growth and differentiation factor 15 (GDF-15) is associated with muscle, fat, and bone metabolism; however, this association has not been well characterized. Plasma GDF-15, appendicular skeletal muscle mass (ASM), fat mass (FM), and bone mineral… read more here.
Keywords: muscle; differentiation factor; bone; growth differentiation ... See more keywords
Soluble neprilysin, NT-proBNP, and growth differentiation factor-15 as biomarkers for heart failure in dialysis patients (SONGBIRD)
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Research in Cardiology"
DOI: 10.1007/s00392-020-01597-x
Abstract: Background Dialysis patients are at increased risk of HF. However, diagnostic utility of NT-proBNP as a biomarker is decreased in patients on dialysis. GDF-15 and cNEP are biomarkers of distinct mechanisms that may contribute to… read more here.
Keywords: differentiation factor; growth differentiation; heart failure; dialysis patients ... See more keywords
Biomechanical stress in myocardial infarctions: can endothelin-1 and growth differentiation factor 15 serve as immunohistochemical markers?
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-017-1726-z
Abstract: Myocardial infarctions go along with biomechanical stress, i.e. stretching of muscle fibres, and the expression of certain marker molecules. We tested if two of those markers, endothelin-1 (ET-1) and growth differentiation factor 15 (GDF-15), can… read more here.
Keywords: myocardial infarctions; endothelin growth; immunohistochemical markers; differentiation factor ... See more keywords
A recurrent, non-penetrant sequence variant, p.Arg266Cys in Growth/Differentiation Factor 3 (GDF3) in a female with unilateral anophthalmia and skeletal anomalies
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2017.06.006
Abstract: Purpose The genetic causes of anophthalmia, microphthalmia and coloboma remain poorly understood. Missense mutations in Growth/Differentiation Factor 3 (GDF3) gene have previously been reported in patients with microphthalmia, iridial and retinal colobomas, Klippel-Feil anomaly with… read more here.
Keywords: factor gdf3; differentiation factor; female unilateral; unilateral anophthalmia ... See more keywords