Abstract 2557: Targeting the IGF1R signaling pathway inhibits cell growth and dissemination in BCOR mutant retinoblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2557
Abstract: Retinoblastoma is the most common intraocular cancer of childhood, with approximately 8,000 new cases each year worldwide. While survival rates are relatively high in developed countries, death can occur in up to half of children… read more here.
Keywords: growth dissemination; igf1r signaling; bcor; retinoblastoma ... See more keywords
Copper-Dependent Kinases and Their Role in Cancer Inception, Progression and Metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101520
Abstract: In recent years, copper function has been expanded beyond its consolidated role as a cofactor of enzyme catalysis. Recent papers have demonstrated a new dynamic role for copper in the regulation of cell signaling pathways… read more here.
Keywords: growth dissemination; copper dependent; copper; role ... See more keywords