A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans
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DOI: 10.1002/2211-5463.13470
Abstract: Recent biochemical experiments have indicated that in Candida albicans, a commensal fungal pathogen, the Ras signaling pathway plays a significant role in the yeast‐to‐hyphal transition; specifically, two enzymes in this pathway, Adenyl Cyclase Cyr1 and GTPase… read more here.
Keywords: bistable switch; adenyl cyclase; switch; cyclase cyr1 ... See more keywords
Antimicrobial Compounds Produced by Vaginal Lactobacillus crispatus Are Able to Strongly Inhibit Candida albicans Growth, Hyphal Formation and Regulate Virulence-related Gene Expressions
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DOI: 10.3389/fmicb.2017.00564
Abstract: The female vaginal environment contains diverse microorganisms, and their interactions play significant roles in health and disease. Lactobacillus species are the predominant vaginal microorganisms in healthy women and relevant as a barrier to defense against… read more here.
Keywords: antimicrobial compounds; hyphal formation; growth hyphal; growth ... See more keywords