Growing Pains: The Need for Engineered Platforms to Study Growth Plate Biology
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200471
Abstract: Growth plates, or physis, are highly specialized cartilage tissues responsible for longitudinal bone growth in children and adolescents. Chondrocytes that reside in growth plates are organized into three distinct zones essential for proper function. Modeling… read more here.
Keywords: growing pains; growth; growth plate; growth plates ... See more keywords
Birth injuries to growth plates: A sheep in wolves' clothing
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DOI: 10.1002/jcu.22444
Abstract: Growth plate injuries (Salter‐Harris type 1 or physeal fractures) of the long bones in the newborn are easily misdiagnosed as joint fractures with dislocations due to their nonossified epiphyses on plain radiographs. Diagnosis with musculoskeletal… read more here.
Keywords: growth plates; sheep wolves; injuries growth; growth ... See more keywords
Altered IGF-I activity and accelerated bone elongation in growth plates precedes excess weight gain in a mouse model of juvenile obesity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00431.2021
Abstract: Nearly one-third of children in the United States are overweight or obese by their pre-teens. Tall stature and accelerated bone elongation are characteristic features of childhood obesity, which co-occur with conditions such as limb bowing,… read more here.
Keywords: elongation; growth; growth plates; high fat ... See more keywords