The interaction between androgen receptor and semenogelin I: a synthetic LxxLL peptide antagonist inhibits the growth of prostate cancer cells
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DOI: 10.1038/bjc.2017.404
Abstract: Background:We previously demonstrated that a seminal plasma protein, semenogelin I (SgI), functioned as an androgen receptor (AR) coactivator. Meanwhile, several short sequence motifs in AR coregulators, such as LxxLL (L=leucine), have been shown to mediate… read more here.
Keywords: androgen receptor; growth; prostate cancer; growth prostate ... See more keywords
Relationship Between Aerobic Fitness, the Serum IGF-1 Profiles of Healthy Young Adult African American Males, and Growth of Prostate Cancer Cells
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DOI: 10.1177/1557988315587740
Abstract: The growth of prostate tumors is mediated by the bioavailability of androgens and insulin-like growth factors. This study tested the hypothesis that healthy young adult African American men exhibiting low aerobic capacity (fitness) have serum… read more here.
Keywords: fitness group; growth prostate; serum; fitness ... See more keywords